HIV and malnutrition: effects on immune system
S Duggal, TD Chugh, AK Duggal - Journal of Immunology …, 2012 - Wiley Online Library
HIV or human immunodeficiency virus infection has assumed worldwide proportions and
importance in just a span of 25 years. Continuous research is being done in many parts of …
importance in just a span of 25 years. Continuous research is being done in many parts of …
The T-cell response to HIV
B Walker, A McMichael - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
HIV is a disease in which the original clinical observations of severe opportunistic infections
gave the first clues regarding the underlying pathology, namely that HIV is essentially an …
gave the first clues regarding the underlying pathology, namely that HIV is essentially an …
Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection
JM Angelosanto, SD Blackburn, A Crawford… - Journal of …, 2012 - Am Soc Microbiol
ABSTRACT T cell exhaustion and loss of memory potential occur during many chronic viral
infections and cancer. We investigated when during chronic viral infection virus-specific CD8 …
infections and cancer. We investigated when during chronic viral infection virus-specific CD8 …
Absence of HIV-1 evolution in the gut-associated lymphoid tissue from patients on combination antiviral therapy initiated during primary infection
TH Evering, S Mehandru, P Racz… - PLoS …, 2012 - journals.plos.org
Mucosal mononuclear (MMC) CCR5+ CD4+ T cells of the gastrointestinal (GI) tract are
selectively infected and depleted during acute HIV-1 infection. Despite early initiation of …
selectively infected and depleted during acute HIV-1 infection. Despite early initiation of …
Immunovirologic control 24 months after interruption of antiretroviral therapy initiated close to HIV seroconversion
Background There is interest in whether a short course of combination antiretroviral therapy
(cART) at the time of human immunodeficiency virus (HIV) seroconversion could induce long …
(cART) at the time of human immunodeficiency virus (HIV) seroconversion could induce long …
HIV-1 control after transient antiretroviral treatment initiated in primary infection: role of patient characteristics and effect of therapy
C Goujard, I Girault, C Rouzioux, C Lécuroux… - Antiviral …, 2012 - journals.sagepub.com
Background The occurrence of viral control after interruption of an antiretroviral treatment
(ART) initiated during primary HIV-1 infection (PHI) is rare and the frequency and predictive …
(ART) initiated during primary HIV-1 infection (PHI) is rare and the frequency and predictive …
The setpoint study (ACTG A5217): effect of immediate versus deferred antiretroviral therapy on virologic set point in recently HIV-1–infected individuals
CM Hogan, V DeGruttola, X Sun… - Journal of Infectious …, 2012 - academic.oup.com
Abstract (See the editorial commentary by Tossonian and Conway, on pages 10–12.)
Background. The benefits of antiretroviral therapy during early human immunodeficiency …
Background. The benefits of antiretroviral therapy during early human immunodeficiency …
Detection of acute HIV infection: we can't close the window
BM Branson, JD Stekler - Journal of Infectious Diseases, 2012 - academic.oup.com
Acute human immunodeficiency virus (HIV) infection poses a dilemma for diagnosis, clinical
management, and public health. It has been variously defined as the transient symptomatic …
management, and public health. It has been variously defined as the transient symptomatic …
Developing strategies for HIV-1 eradication
CM Durand, JN Blankson, RF Siliciano - Trends in immunology, 2012 - cell.com
Highly active antiretroviral therapy (HAART) suppresses HIV-1 replication, transforming the
outlook for infected patients. However, reservoirs of replication-competent forms of the virus …
outlook for infected patients. However, reservoirs of replication-competent forms of the virus …
No treatment versus 24 or 60 weeks of antiretroviral treatment during primary HIV infection: the randomized Primo-SHM trial
ML Grijsen, R Steingrover, FWNM Wit, S Jurriaans… - PLoS …, 2012 - journals.plos.org
Background The objective of this study was to assess the benefit of temporary combination
antiretroviral therapy (cART) during primary HIV infection (PHI). Methods and Findings Adult …
antiretroviral therapy (cART) during primary HIV infection (PHI). Methods and Findings Adult …