[HTML][HTML] RasGRF1 regulates proliferation and metastatic behavior of human alveolar rhabdomyosarcomas
M Tarnowski, G Schneider… - International …, 2012 - spandidos-publications.com
The involvement of the Ras superfamily of GTPases in the pathogenesis of
rhabdomysarcoma (RMS) is not well understood. While mutant H-Ras leads to embryonal …
rhabdomysarcoma (RMS) is not well understood. While mutant H-Ras leads to embryonal …
Novel RasGRF1-derived Tat-fused peptides inhibiting Ras-dependent proliferation and migration in mouse and human cancer cells
E Sacco, D Metalli, M Spinelli, R Manzoni… - Biotechnology …, 2012 - Elsevier
Mutations of RAS genes are critical events in the pathogenesis of different human tumors
and Ras proteins represent a major clinical target for the development of specific inhibitors …
and Ras proteins represent a major clinical target for the development of specific inhibitors …
Regulation of hSos1 activity is a system-level property generated by its multi-domain structure
The multi-domain protein hSos1 plays a major role in cell growth and differentiation through
its Ras-specific guanine nucleotide exchange domain whose complex regulation involves …
its Ras-specific guanine nucleotide exchange domain whose complex regulation involves …