[HTML][HTML] Structure and composition of pulmonary arteries, capillaries and veins

MI Townsley - Comprehensive Physiology, 2012 - ncbi.nlm.nih.gov
The pulmonary vasculature is comprised of three anatomic compartments connected in
series: the arterial tree, an extensive capillary bed, and the venular tree. Although in general …

Novel risk factors for atrial fibrillation: useful for risk prediction and clinical decision making?

M Rienstra, DD McManus, EJ Benjamin - Circulation, 2012 - Am Heart Assoc
Atrial fibrillation (AF) is the most common cardiac arrhythmia; the lifetime risk is 1 in 4 for
persons over the age of 40 years in the United States. 1 AF is associated with an increased …

Symptomatic response to antiarrhythmic drug therapy is modulated by a common single nucleotide polymorphism in atrial fibrillation

B Parvez, J Vaglio, S Rowan, R Muhammad… - Journal of the American …, 2012 - jacc.org
Objectives: This study tested the hypothesis that response to antiarrhythmic drugs (AADs) is
modulated by 3 common loci associated with atrial fibrillation (AF). Background: Recent …

Chromosome 4q25 variants are genetic modifiers of rare ion channel mutations associated with familial atrial fibrillation

MD Ritchie, S Rowan, G Kucera, T Stubblefield… - Journal of the American …, 2012 - jacc.org
Objectives: The aim of this study was to test the hypothesis that 2 common polymorphisms in
the chromosome 4q25 region that have been associated with atrial fibrillation (AF) contribute …

An introduction to murine models of atrial fibrillation

G Riley, F Syeda, P Kirchhof, L Fabritz - Frontiers in physiology, 2012 - frontiersin.org
Understanding the mechanism of re-entrant arrhythmias in the past 30 years has allowed
the development of almost curative therapies for many rhythm disturbances. The complex …

Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing

F Lescroart, T Mohun, SM Meilhac, M Bennett… - Circulation …, 2012 - Am Heart Assoc
Rationale: Genetic tracing experiments and cell lineage analyses are complementary
approaches that give information about the progenitor cells of a tissue. Approaches based …

Genetic loci on chromosomes 4q25, 7p31, and 12p12 are associated with onset of lone atrial fibrillation before the age of 40 years

MS Olesen, AG Holst, J Jabbari, JB Nielsen… - Canadian Journal of …, 2012 - Elsevier
Background Three distinct genetic loci on chromosomes 1q21, 4q25, and 16q22 have been
associated with atrial fibrillation (AF) in genome-wide association studies (GWAS). Five …

Mutation spectrum of the GATA4 gene in patients with idiopathic atrial fibrillation

J Wang, YM Sun, YQ Yang - Molecular biology reports, 2012 - Springer
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia associated with
substantially increased morbidity and mortality. Growing evidence strongly implicates …

Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation

J Li, WD Liu, ZL Yang, YQ Yang - … journal of molecular …, 2012 - spandidos-publications.com
Atrial fibrillation (AF) is the most commonly sustained cardiac arrhythmia, and confers a
substantially increased risk of morbidity and mortality. Increasing evidence has indicated …

New advances in the genetic basis of atrial fibrillation

S Mahida, PT Ellinor - Journal of cardiovascular …, 2012 - Wiley Online Library
New Genetic Loci for Atrial Fibrillation. Over the past decade, compelling evidence has
emerged from population‐based studies to suggest that AF is a heritable disease. More …