Challenges in design of translational nanocarriers

Q Sun, M Radosz, Y Shen - Journal of controlled release, 2012 - Elsevier
Cancer drug delivery achieving high therapeutic efficacy and low side effects requires a
nanocarrier to tightly retain the drug, efficiently reach the tumor, then quickly enter the tumor …

[HTML][HTML] Nanocapsules: the weapons for novel drug delivery systems

P Kothamasu, H Kanumur, N Ravur, C Maddu… - BioImpacts …, 2012 - ncbi.nlm.nih.gov
Methods Various technical approaches are utilized for obtaining the nanocapsules;
however, the methods of interfacial polymerization for monomer and the nano-deposition for …

Biodegradable polymer-curcumin conjugate micelles enhance the loading and delivery of low-potency curcumin

R Yang, S Zhang, D Kong, X Gao, Y Zhao… - Pharmaceutical …, 2012 - Springer
Purpose To utilize a novel type of polymer-drug conjugate micelle to enhance the delivery of
low-potency curcumin. Methods Multiple curcumin molecules were conjugated to poly (lactic …

The inhibition of tumor growth and metastasis by self-assembled nanofibers of taxol

H Wang, J Wei, C Yang, H Zhao, D Li, Z Yin, Z Yang - Biomaterials, 2012 - Elsevier
Molecular hydrogels have big potential for local delivery and sustained release of
therapeutic agents. In this paper, we reported on a molecular hydrogel mainly formed by the …

Multifunctional pH-disintegrable micellar nanoparticles of asymmetrically functionalized β-cyclodextrin-based star copolymer covalently conjugated with doxorubicin …

T Liu, X Li, Y Qian, X Hu, S Liu - Biomaterials, 2012 - Elsevier
We report on a novel type of multifunctional pH-disintegrable micellar nanoparticles
fabricated from asymmetrically functionalized β-cyclodextrin (β-CD) based star copolymers …

[PDF][PDF] Rational design of a tetrameric protein to enhance interactions between self‐assembled fibers gives molecular hydrogels

X Zhang, X Chu, L Wang, H Wang, G Liang… - Angewandte …, 2012 - researchgate.net
Molecular hydrogels have attracted extensive research interest in recent years because of
their inherent properties (eg, formation by the self-assembly of small molecules and their gel …

Dextran vesicular carriers for dual encapsulation of hydrophilic and hydrophobic molecules and delivery into cells

PS Pramod, K Takamura, S Chaphekar… - …, 2012 - ACS Publications
Dextran vesicular nanoscaffolds were developed based on polysaccharide and renewable
resource alkyl tail for dual encapsulation of hydrophilic and hydrophobic molecules (or …

Bioreducible polymersomes for intracellular dual-drug delivery

T Thambi, VG Deepagan, H Ko, DS Lee… - Journal of Materials …, 2012 - pubs.rsc.org
Stimuli-sensitive polymersomes, composed of amphiphilic block copolymers, have emerged
as a promising nanocarrier for triggered release of anticancer drugs. In this study, we …

Formation of drug/surfactant catanionic vesicles and their application in sustained drug release

Y Jiang, F Li, Y Luan, W Cao, X Ji, L Zhao… - International journal of …, 2012 - Elsevier
The aggregation behavior of the cationic drug/anionic surfactant vesicles formed by
tetracaine hydrochloride (TH) and double-chain surfactant, sodium bis (2-ethylhexyl) …

Carrier-free, functionalized drug nanoparticles for targeted drug delivery

W Li, Y Yang, C Wang, Z Liu, X Zhang, F An… - Chemical …, 2012 - pubs.rsc.org
Carrier-free, functionalized drug nanoparticles for targeted drug delivery - Chemical
Communications (RSC Publishing) DOI:10.1039/C2CC33214K Royal Society of Chemistry …