Divergence and convergence in enzyme evolution: parallel evolution of paraoxonases from quorum-quenching lactonases
We discuss the basic features of divergent versus convergent evolution and of the common
scenario of parallel evolution. The example of quorum-quenching lactonases is …
scenario of parallel evolution. The example of quorum-quenching lactonases is …
Evaluation of hydropathy of amino acids from a comparison of their viscosities inside vesicles and on supported lipid bilayers
K Sankaranarayanan, A Dhathathreyan - Colloids and Surfaces B …, 2012 - Elsevier
The viscosity of amino acids enclosed in giant lipid vesicles (ηout) subjected to a shear flow
near a solid surface has been studied using quartz crystal microbalance (QCM). This …
near a solid surface has been studied using quartz crystal microbalance (QCM). This …
Contrast variation
DM Engelman, PB Moore - 2012 - Wiley Online Library
The principle of contrast variation was studied in early work by Bragg & Perutz (1952 [link]),
who observed that the magnitudes of low-order reflections in X-ray studies of protein crystals …
who observed that the magnitudes of low-order reflections in X-ray studies of protein crystals …
Variation of internal contrast
DM Engelman, PB Moore - 2012 - Wiley Online Library
A second form of contrast variation can be achieved by replacing the hydrogen atoms in
biological molecules with deuterium. If, in addition, it is possible to deuterate selected …
biological molecules with deuterium. If, in addition, it is possible to deuterate selected …
Small-angle neutron scattering
DM Engelman, PB Moore - 2012 - Wiley Online Library
The use of small-angle neutron scattering (SANS) for the study of biological macromolecules
is described. Topics covered in this chapter include: the theoretical basis of SANS; contrast …
is described. Topics covered in this chapter include: the theoretical basis of SANS; contrast …