Plasticity in reflex pathways to the lower urinary tract following spinal cord injury

WC de Groat, N Yoshimura - Experimental neurology, 2012 - Elsevier
The lower urinary tract has two main functions, storage and periodic expulsion of urine, that
are regulated by a complex neural control system in the brain and lumbosacral spinal cord …

Neurotrophins as regulators of urinary bladder function

P Ochodnicky, CD Cruz, N Yoshimura… - Nature Reviews Urology, 2012 - nature.com
Increased voiding frequency and urgency are among the most prevalent storage lower
urinary tract symptoms (LUTS), often diagnosed as part of overactive bladder syndrome …

[PDF][PDF] Intravesical onabotulinumtoxinA injections for refractory painful bladder syndrome

MD Shiu-Dong Chung, MD Yuh-Chen Kuo… - Pain …, 2012 - painphysicianjournal.com
Background: Bladder pain associated with interstitial cystitis and painful bladder syndrome
(IC/PBS) is frequently excruciating and intractable. The use of onabotulinumtoxinA (BoNT-A) …

Transient receptor potential vanilloid 1 mediates nerve growth factor‐induced bladder hyperactivity and noxious input

B Frias, A Charrua, A Avelino, MC Michel… - BJU …, 2012 - Wiley Online Library
What's known on the subject? and What does the study add? The interaction between the
TRPV1 and NGF systems has been addressed only in the context of acute somatic pain. The …

Effects of CYP-induced cystitis on PACAP/VIP and receptor expression in micturition pathways and bladder function in mice with overexpression of NGF in urothelium

BM Girard, JD Tompkins, RL Parsons, V May… - Journal of Molecular …, 2012 - Springer
We have previously demonstrated nerve growth factor (NGF) regulation of pituitary
adenylate cyclase-activating polypeptide (PACAP)/receptors in bladder reflex pathways …

Autonomic dysfunction and plasticity in micturition reflexes in human α‐synuclein mice

RW Hamill, JD Tompkins, BM Girard… - Developmental …, 2012 - Wiley Online Library
Although often overshadowed by the motor dysfunction associated with Parkinson's disease
(PD), autonomic dysfunction including urinary bladder and bowel dysfunctions are often …

[HTML][HTML] Long-term anodal block stimulation at sacral anterior roots promoted recovery of neurogenic bladder function in a rabbit model of complete spinal cord injury …

X Wang, Q Gao, X Yang, W Wang, X Gu… - Neural Regeneration …, 2012 - journals.lww.com
A complete spinal cord injury model was established in experimental rabbits using the
spinal cord clip compression method. Urodynamic examination was performed 2 weeks later …

[PDF][PDF] Chapter Biomarkers in the Overactive Bladder Syndrome

C Silva, T Antunes Lopes, F Cruz, CD Cruz - 2012 - library.oapen.org
Overactive bladder (OAB) is a symptomatic complex affecting both men and women. The
overall incidence is above 10% but may exceed 40% in the elderly population (Irwin et al …

[PDF][PDF] Novos Biomarcadores no Síndrome de Bexiga Hiperactiva: à procura de um instrumento objectivo

T Antunes-Lopes, S Carvalho-Barros, C Duarte-Cruz… - apurologia.pt
O síndrome de bexiga hiperactiva (SBH) é uma patologia muito prevalente, com custos
socio-económicos consideráveis. O diagnóstico de SBH é clínico e subjectivo. Até à data …