Mitochondria perform diverse yet interconnected functions, producing ATP and many
biosynthetic intermediates while also contributing to cellular stress responses such as …

The discovery of the sensory nature of the carotid body dates back to the beginning of the
20th century. Following these seminal discoveries, research into carotid body mechanisms …

The AMP-activated protein kinase (AMPK) is a sensor of cellular energy status. It is
activated, by a mechanism requiring the tumor suppressor LKB1, by metabolic stresses that …

The hydrolysis of ATP drives virtually all of the energy-requiring processes in living cells. A
prerequisite of living cells is that the concentration of ATP needs to be maintained at …

The adenosine monophosphate-activated protein kinase (AMPK) is a metabolic sensor of
energy metabolism at the cellular as well as whole-body level. It is activated by low energy …

Ischemic heart disease is a significant cause of morbidity and mortality in Western society.
Although interventions, such as thrombolysis and percutaneous coronary intervention, have …

AMPK (AMP-activated protein kinase) is one of the key players in maintaining intracellular
homoeostasis. AMPK is well known as an energy sensor and can be activated by increased …

The energy sensor AMP-activated protein kinase (AMPK) is activated by metabolic stress
and restores ATP levels in cells by switching off anabolic and switching on catabolic …

Catecholamine-stimulated lipolysis occurs by activating adenylate cyclase and raising cAMP
levels, thereby increasing protein kinase A (PKA) activity. This results in phosphorylation …

Resveratrol has been reported to increase adrenaline-induced lipolysis in 3T3-L1
adipocytes. The general aim of the present work was to gain more insight concerning the …