Hyperthermia-triggered drug delivery from temperature-sensitive liposomes using MRI-guided high intensity focused ultrasound

H Grüll, S Langereis - Journal of Controlled Release, 2012 - Elsevier
In the continuous search for cancer therapies with a higher therapeutic window, localized
temperature-induced drug delivery may offer a minimal invasive treatment option. Here, a …

Phase‐shift, stimuli‐responsive perfluorocarbon nanodroplets for drug delivery to cancer

N Rapoport - Wiley Interdisciplinary Reviews: Nanomedicine …, 2012 - Wiley Online Library
This review focuses on phase‐shift perfluorocarbon nanoemulsions whose action depends
on an ultrasound‐triggered phase shift from a liquid to gas state. For drug‐loaded …

20 years of ultrasound contrast agent modeling

T Faez, M Emmer, K Kooiman… - IEEE transactions on …, 2012 - ieeexplore.ieee.org
The merits of ultrasound contrast agents (UCAs) were already known in the 1960s. It was,
however, not until the 1990s that UCAs were clinically approved and marketed. In these …

Polyplex-microbubble hybrids for ultrasound-guided plasmid DNA delivery to solid tumors

SR Sirsi, SL Hernandez, L Zielinski, H Blomback… - Journal of controlled …, 2012 - Elsevier
Microbubble ultrasound contrast agents are being developed as image-guided gene
carriers for targeted delivery in vivo. In this study, novel polyplex-microbubbles were …

Designing switchable nanosystems for medical application

R Lehner, X Wang, M Wolf, P Hunziker - Journal of controlled release, 2012 - Elsevier
Within the last decade, nanotechnology has had a major impact on preclinical development
in medicine, shaping the emerging scientific field of nanomedicine. Diverse nanomaterial …

[HTML][HTML] Ultrasound biomicroscopy in small animal research: applications in molecular and preclinical imaging

A Greco, M Mancini, S Gargiulo… - BioMed Research …, 2012 - hindawi.com
Ultrasound biomicroscopy (UBM) is a noninvasive multimodality technique that allows high-
resolution imaging in mice. It is affordable, widely available, and portable. When it is coupled …

A self-assembled delivery platform with post-production tunable release rate

J Boekhoven, M Koot, TA Wezendonk… - Journal of the …, 2012 - ACS Publications
Self-assembly of three molecular components results in a delivery platform, the release rate
of which can be tuned after its production. A fluorophore-conjugated gelator can be …

Emulsion templating of poly (lactic acid) particles: droplet formation behavior

GT Vladisavljević, WJ Duncanson, HC Shum… - Langmuir, 2012 - ACS Publications
Monodisperse poly (dl-lactic acid)(PLA) particles of diameters between 11 and 121 μm were
fabricated in flow focusing glass microcapillary devices by evaporation of dichloromethane …

Microbubbles with surface coated by superparamagnetic iron oxide nanoparticles

W He, F Yang, Y Wu, S Wen, P Chen, Y Zhang, N Gu - Materials letters, 2012 - Elsevier
Microbubbles (MBs) with the ability of enhancing ultrasound image contrast and delivering
drugs are widely used in medical applications. By combining microbubbles and …

Applications of polymeric micelles with tumor targeted in chemotherapy

H Ding, X Wang, S Zhang, X Liu - Journal of Nanoparticle Research, 2012 - Springer
Polymeric micelles (PMs) have gained more progress as a carrier system with the quick
development of biological and nanoparticle techniques. In particular, PMs with smart …