[HTML][HTML] Cell migration
Cell migration is fundamental to establishing and maintaining the proper organization of
multicellular organisms. Morphogenesis can be viewed as a consequence, in part, of cell …
multicellular organisms. Morphogenesis can be viewed as a consequence, in part, of cell …
Nonpolarized signaling reveals two distinct modes of 3D cell migration
We search in this paper for context-specific modes of three-dimensional (3D) cell migration
using imaging for phosphatidylinositol (3, 4, 5)-trisphosphate (PIP3) and active Rac1 and …
using imaging for phosphatidylinositol (3, 4, 5)-trisphosphate (PIP3) and active Rac1 and …
Stiffness-controlled three-dimensional extracellular matrices for high-resolution imaging of cell behavior
Regulation of cell functions by the physical properties of the extracellular matrix (ECM) has
emerged as a crucial contributor to development and disease. Two specific physical …
emerged as a crucial contributor to development and disease. Two specific physical …
Hic-5 promotes invadopodia formation and invasion during TGF-β–induced epithelial–mesenchymal transition
J Pignatelli, DA Tumbarello, RP Schmidt… - Journal of Cell …, 2012 - rupress.org
Transforming growth factor β (TGF-β)–stimulated epithelial–mesenchymal transition (EMT) is
an important developmental process that has also been implicated in increased cell …
an important developmental process that has also been implicated in increased cell …
IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling
N Stöhr, M Köhn, M Lederer, M Glaß… - Genes & …, 2012 - genesdev.cshlp.org
In primary neurons, the oncofetal RNA-binding protein IGF2BP1 (IGF2 mRNA-binding
protein 1) controls spatially restricted β-actin (ACTB) mRNA translation and modulates …
protein 1) controls spatially restricted β-actin (ACTB) mRNA translation and modulates …
Micro-environmental control of cell migration–myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics
AD Doyle, ML Kutys, MA Conti… - Journal of cell …, 2012 - journals.biologists.com
Recent evidence suggests that organization of the extracellular matrix (ECM) into aligned
fibrils or fibril-like ECM topographies promotes rapid migration in fibroblasts. However, the …
fibrils or fibril-like ECM topographies promotes rapid migration in fibroblasts. However, the …
Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism
Mesenchymal cell migration as exhibited by fibroblasts is distinct from amoeboid cell
migration and is characterized by dynamic competition among multiple protrusions, which …
migration and is characterized by dynamic competition among multiple protrusions, which …
Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners
Spontaneous molecular oscillations are ubiquitous in biology. But to our knowledge,
periodic cell migratory patterns have not been observed. Here we report the highly regular …
periodic cell migratory patterns have not been observed. Here we report the highly regular …
The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility
M Ishida-Takagishi, A Enomoto, N Asai… - Nature …, 2012 - nature.com
Dishevelled is the common mediator of canonical and non-canonical Wnt signalling
pathways, which are important for embryonic development, tissue maintenance and cancer …
pathways, which are important for embryonic development, tissue maintenance and cancer …
Nuclear transport receptor karyopherin-α2 promotes malignant breast cancer phenotypes in vitro
E Noetzel, M Rose, J Bornemann, M Gajewski… - Oncogene, 2012 - nature.com
Tumorigenesis and tumor progression are associated with dysfunction of the nuclear
transport machinery at the level of import and export receptors (karyopherins). Recent …
transport machinery at the level of import and export receptors (karyopherins). Recent …