The cellular and signaling networks linking the immune system and metabolism in disease

O Osborn, JM Olefsky - Nature medicine, 2012 - nature.com
It is now recognized that obesity is driving the type 2 diabetes epidemic in Western
countries. Obesity-associated chronic tissue inflammation is a key contributing factor to type …

Inflammatory cytokines in experimental and human stroke

KL Lambertsen, K Biber… - Journal of Cerebral Blood …, 2012 - journals.sagepub.com
Inflammation is a hallmark of stroke pathology. The cytokines, tumor necrosis factor (TNF),
interleukin (IL)-1, and IL-6, modulate tissue injury in experimental stroke and are therefore …

Effects of a 1-year supplementation with cholecalciferol on interleukin-6, tumor necrosis factor-alpha and insulin resistance in overweight and obese subjects

J Beilfuss, V Berg, M Sneve, R Jorde, E Kamycheva - Cytokine, 2012 - Elsevier
Insufficient vitamin D status has been linked to autoimmune diseases, cancer and metabolic
disorders, like obesity and insulin resistance. In vitro and animal studies suggest that vitamin …

Systematic review of proinflammatory cytokines in obsessive-compulsive disorder

SM Gray, MH Bloch - Current psychiatry reports, 2012 - Springer
Several studies have examined levels of proinflammatory cytokines, such as tumor necrosis
factor (TNF)-α, interleukin (IL)-1β, and IL-6. This meta-analysis was conducted to examine …

Interleukin-6 is a potential biomarker for severe pandemic H1N1 influenza A infection

SG Paquette, D Banner, Z Zhao, Y Fang, SSH Huang… - PloS one, 2012 - journals.plos.org
Pandemic H1N1 influenza A (H1N1pdm) is currently a dominant circulating influenza strain
worldwide. Severe cases of H1N1pdm infection are characterized by prolonged activation of …

Exercise pre-conditioning reduces brain inflammation and protects against toxicity induced by traumatic brain injury: behavioral and neurochemical approach

BC Mota, L Pereira, MA Souza, LFA Silva… - Neurotoxicity …, 2012 - Springer
Although the favorable effects of physical exercise in neurorehabilitation after traumatic
brain injury (TBI) are well known, detailed pathologic and functional alterations exerted by …

High-dose curcuminoids are efficacious in the reduction in symptoms and signs of oral lichen planus

N Chainani-Wu, E Madden, F Lozada-Nur… - Journal of the American …, 2012 - Elsevier
BACKGROUND: Curcuminoids are components of turmeric (Curcuma longa) that possess
anti-inflammatory properties. OBJECTIVE: We sought to study the efficacy of curcuminoids in …

Local and systemic pro-inflammatory and anti-inflammatory cytokine patterns in patients with chronic subdural hematoma: a prospective study

M Stanisic, AO Aasen, AH Pripp, KF Lindegaard… - Inflammation …, 2012 - Springer
Objective and design Innate immune pro-and anti-inflammatory responses in patients with
chronic subdural hematoma (CSDH) were investigated by measuring and comparing the …

LPS-induced release of IL-6 from glia modulates production of IL-1β in a JAK2-dependent manner

AM Minogue, JP Barrett, MA Lynch - Journal of neuroinflammation, 2012 - Springer
Background Compelling evidence has implicated neuroinflammation in the pathogenesis of
a number of neurodegenerative conditions. Chronic activation of both astrocytes and …

Protective effects of aerobic exercise on acute lung injury induced by LPS in mice

CT Reis Goncalves, CG Reis Goncalves… - Critical Care, 2012 - Springer
Introduction The regular practice of physical exercise has been associated with beneficial
effects on various pulmonary conditions. We investigated the mechanisms involved in the …