Xenogeneic silencing proteins facilitate horizontal gene transfer by silencing expression of
AT-rich sequences. By virtue of their activity these proteins serve as master regulators of a …

Abstract Significance: Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis
(TB), can persist in a latent state for decades without causing overt disease. Since latent Mtb …

Coordination of the onset of flowering with developmental status and seasonal cues is
critical for reproductive success in plants. Molecular genetic studies on Arabidopsis mutants …

Microscale thermophoresis (MST) is a new method that enables the quantitative analysis of
molecular interactions in solution at the microliter scale. The technique is based on the …

Human ASXL proteins, orthologs of Drosophila Additional Sex combs, have been implicated
in conjunction with TET2 as a major target for mutations and translocations leading to a wide …

Acquisition of self-renewal capability by myeloid progenitors to become leukemic stem cells
during myeloid leukemia development is poorly understood. Here, we show that Setbp1 …

We provide a portrait of the bacterial transcription apparatus in light of the data emerging
from structural studies, sequence analysis and comparative genomics to bring out important …

Transcriptional regulation requires co-ordinated action of transcription factors, co-activator
complexes and general transcription factors to access specific loci in the dense chromatin …

The regulation of nucleosome positioning and composition by ATP-dependent chromatin
remodeling enzymes and their associated binding partners plays important biological roles …

Meiotically heritable epigenetic changes in gene regulation known as paramutations are
facilitated by poorly understood trans-homolog interactions. Mutations affecting …