NK cells: key to success of DC-based cancer vaccines?
E Lion, ELJM Smits, ZN Berneman… - The …, 2012 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to:
Describe the current in vivo experimental and clinical dendritic cell (DC) vaccination studies …
Describe the current in vivo experimental and clinical dendritic cell (DC) vaccination studies …
Altered functions of natural killer cells in response to L-Arginine availability
B Lamas, J Vergnaud-Gauduchon… - Cellular …, 2012 - Elsevier
L-Arginine (L-Arg) availability is crucial in the regulation of immune response. Indeed, L-Arg
deficiency induces T-cell dysfunction and could modulate the properties of natural killer (NK) …
deficiency induces T-cell dysfunction and could modulate the properties of natural killer (NK) …
[HTML][HTML] Tyrosine kinase Btk is required for NK cell activation
Y Bao, J Zheng, C Han, J Jin, H Han, Y Liu… - Journal of Biological …, 2012 - ASBMB
Bruton tyrosine kinase (Btk) is not only critical for B cell development and differentiation but
is also involved in the regulation of Toll-like receptor-triggered innate response of …
is also involved in the regulation of Toll-like receptor-triggered innate response of …
Herpes simplex virus antigens directly activate NK cells via TLR2, thus facilitating their presentation to CD4 T lymphocytes
NK cells infiltrate human herpetic lesions, but their role has been underexplored. HSV can
stimulate innate immune responses via surface TLR2, which is expressed on monocyte …
stimulate innate immune responses via surface TLR2, which is expressed on monocyte …
Natural killer cell degranulation capacity predicts early onset of the immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients with tuberculosis
Immune reconstitution inflammatory syndrome (IRIS) is a common and potentially serious
complication occurring in HIV-infected patients being treated for tuberculosis (TB) using …
complication occurring in HIV-infected patients being treated for tuberculosis (TB) using …
[HTML][HTML] Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development
CI Domaica, MB Fuertes, I Uriarte, MV Girart… - PLoS …, 2012 - journals.plos.org
Two populations of human natural killer (NK) cells can be identified in peripheral blood. The
majority are CD3− CD56dim cells while the minority exhibits a CD3− CD56bright phenotype …
majority are CD3− CD56dim cells while the minority exhibits a CD3− CD56bright phenotype …
Type 2 Innate Lymphoid Cells: Friends or Foes—Role in Airway Allergic Inflammation and Asthma
Innate‐like lymphocytes (ILLs) and innate lymphoid cells (ILCs) are two newly characterized
families of lymphocytes with limited and no rearranged antigen receptors, respectively …
families of lymphocytes with limited and no rearranged antigen receptors, respectively …
[HTML][HTML] Kinome analysis of receptor-induced phosphorylation in human natural killer cells
S König, M Nimtz, M Scheiter, HG Ljunggren… - PLoS …, 2012 - journals.plos.org
Background Natural killer (NK) cells contribute to the defense against infected and
transformed cells through the engagement of multiple germline-encoded activation …
transformed cells through the engagement of multiple germline-encoded activation …
天然免疫自然杀伤细胞在糖尿病发病及发生发展中的研究进展
徐兵川， 郭晖 - 中国全科医学, 2012 - cqvip.com
糖尿病是全世界许多国家的常见病和多发病, 而其发病机制迄今尚未明确. 虽然越来越多的证据
显示免疫机制在其发病及发展的过程中起着重要作用, 但是仍未形成统一的理论. 长期以来 …
显示免疫机制在其发病及发展的过程中起着重要作用, 但是仍未形成统一的理论. 长期以来 …
胸腺肽α1 联合奥沙利铂和卡培他滨方案在结直肠癌术后患者辅助化疗中的应用
戴夕超， 张西志， 汪步海 - 临床和实验医学杂志, 2012 - cqvip.com
目的观察结直肠癌术后患者采用奥沙利铂和卡培他滨化疗联合胸腺肽α1 的近期反应. 方法将64
例就诊的结直肠癌术后患者随机分为两组, 实验组: 采用奥沙利铂+ 卡培他滨(Xelox) …
例就诊的结直肠癌术后患者随机分为两组, 实验组: 采用奥沙利铂+ 卡培他滨(Xelox) …