Degradation of tau protein by autophagy and proteasomal pathways

Y Wang, E Mandelkow - Biochemical Society Transactions, 2012 - portlandpress.com
Tau aggregates are present in several neurodegenerative diseases and correlate with the
severity of memory deficit in AD (Alzheimer's disease). However, the triggers of tau …

Lysosomal Fusion Dysfunction as a Unifying Hypothesis for Alzheimer′ s Disease Pathology

KE Funk, J Kuret - International journal of Alzheimer's disease, 2012 - Wiley Online Library
Alzheimer′ s disease is characterized pathologically by extracellular senile plaques,
intracellular neurofibrillary tangles, and granulovacuolar degeneration. It has been debated …

脱氧核糖核酸甲基化在阿尔茨海默病发病机制中的研究进展

王淑, 周春奎, 贾建平, 秦伟 - 中华神经科杂志, 2012 - cqvip.com
阿尔茨海默病(Alzheimer's disease, AD) 是一种以进行性认知功能障碍和行为损害为特征的
中枢神经系统退行性病变, 其典型病理改变是B· 淀粉样蛋白(amyloid—β, Aβ) …

[图书][B] Alzheimer's Disease Pathology as a Clue to Pathogenesis

KE Funk - 2012 - search.proquest.com
Alzheimer's disease is characterized pathologically by two intracellular lesions,
granulovacuolar degeneration and neurofibrillary tangles. Because Alzheimer's disease is …