Seizures in low-grade gliomas: natural history, pathogenesis, and outcome after treatments

R Ruda, L Bello, H Duffau, R Soffietti - Neuro-oncology, 2012 - academic.oup.com
Seizures represent a common symptom in low-grade gliomas; when uncontrolled, they
significantly contribute to patient morbidity and negatively impact quality of life. Tumor …

[HTML][HTML] The value of glioma extent of resection in the modern neurosurgical era

DA Hardesty, N Sanai - Frontiers in neurology, 2012 - frontiersin.org
Objective: There remains no general consensus in the neurosurgical oncology literature
regarding the role of extent of glioma resection in improving patient outcome. Although the …

Low-grade glioma surgery in eloquent areas: volumetric analysis of extent of resection and its impact on overall survival. A single-institution experience in 190 patients

T Ius, M Isola, R Budai, G Pauletto, B Tomasino… - Journal of …, 2012 - thejns.org
Object A growing number of published studies have recently demonstrated the role of
resection in overall survival (OS) for patients with gliomas. In this retrospective study, the …

[HTML][HTML] IDH1/2 mutations in WHO grade II astrocytomas associated with localization and seizure as the initial symptom

F Stockhammer, M Misch, HJ Helms, U Lengler, F Prall… - Seizure, 2012 - Elsevier
INTRODUCTION: Seizures are the most common initial symptom in patients with low-grade
glioma and their occurrence strongly depends on the tumor location. The majority of low …

Natural history and surgical management of incidentally discovered low-grade gliomas

MB Potts, JS Smith, AM Molinaro, MS Berger - Journal of neurosurgery, 2012 - thejns.org
Object Low-grade gliomas (LGGs) are rarely diagnosed as an incidental, asymptomatic
finding, and it is not known how the early surgical management of these tumors might affect …

Neurocognitive functioning in adult WHO grade II gliomas: impact of old and new treatment modalities

M Klein - Neuro-oncology, 2012 - academic.oup.com
In the treatment of patients with low-grade glioma, there still is controversy on how surgical
intervention, radiation therapy, and chemotherapy contribute to an ameliorated progression …

Recent surgical management of gliomas

N Sanai, MS Berger - Adv Exp Med Biol, 2012 - Springer
Refinement of neurosurgical technique has enabled safer operations with more aggressive
outcomes. One cornerstone of modern-day practice is the utilization of intraoperative …

The assessment of prognostic factors in surgical treatment of low-grade gliomas: a prospective study

K Majchrzak, W Kaspera, B Bobek-Billewicz… - Clinical neurology and …, 2012 - Elsevier
OBJECTIVE: A prospective volumetric analysis of extent of resection (EOR) was carried out
to assess surgical outcomes in adults diagnosed with hemispheric low grade gliomas …

Emerging operative strategies in neurosurgical oncology

N Sanai - Current opinion in neurology, 2012 - journals.lww.com
Neurosurgical intervention remains the first step in effective glioma management. With
intraoperative mapping techniques, aggressive microsurgical resection can be safely …

[HTML][HTML] Significance of miR-196b in tumor-related epilepsy of patients with gliomas

G You, W Yan, W Zhang, Y Wang, Z Bao, S Li, S Li, G Li… - 2012 - journals.plos.org
Objectives Seizure is a common presenting symptom of primary brain tumors. There are no
published studies regarding the roles of MicroRNA (miRNA) in tumor-related epilepsy. The …