Autophagy: a multifaceted intracellular system for bulk and selective recycling

F Li, RD Vierstra - Trends in plant science, 2012 - cell.com
Plants have evolved sophisticated mechanisms to recycle intracellular constituents. One
gaining in appreciation is autophagy, which involves specialized vesicles engulfing and …

Emerging role of autophagy in kidney function, diseases and aging

TB Huber, CL Edelstein, B Hartleben, K Inoki, M Jiang… - Autophagy, 2012 - Taylor & Francis
Autophagy is a highly conserved process that degrades cellular long-lived proteins and
organelles. Accumulating evidence indicates that autophagy plays a critical role in kidney …

Plant natural compounds: targeting pathways of autophagy as anti‐cancer therapeutic agents

X Zhang, LX Chen, L Ouyang, Y Cheng… - Cell proliferation, 2012 - Wiley Online Library
Natural compounds derived from plant sources are well characterized as possessing a wide
variety of remarkable anti‐tumour properties, for example modulating programmed cell …

Autophagy and pancreatitis

AS Gukovskaya, I Gukovsky - American Journal of …, 2012 - journals.physiology.org
Acute pancreatitis is an inflammatory disease of the exocrine pancreas that carries
considerable morbidity and mortality; its pathophysiology remains poorly understood …

Beginning to understand autophagy, an intracellular self-degradation system in plants

K Yoshimoto - Plant and Cell Physiology, 2012 - academic.oup.com
Autophagy is an evolutionarily conserved intracellular process for the vacuolar degradation
of cytoplasmic components. There is no doubt that autophagy is very important to plant life …

Porcine reproductive and respiratory syndrome virus induces autophagy to promote virus replication

MX Sun, L Huang, R Wang, YL Yu, C Li, PP Li, XC Hu… - Autophagy, 2012 - Taylor & Francis
An increasing number of studies demonstrate that autophagy, an intrinsic mechanism that
can degrade cytoplasmic components, is involved in the infection processes of a variety of …

Ume6 transcription factor is part of a signaling cascade that regulates autophagy

CR Bartholomew, T Suzuki, Z Du… - Proceedings of the …, 2012 - National Acad Sciences
Autophagy has been implicated in a number of physiological processes important for human
heath and disease. Autophagy involves the formation of a double-membrane cytosolic …

MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins

D Colecchia, A Strambi, S Sanzone, C Iavarone… - Autophagy, 2012 - Taylor & Francis
Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved
catabolic process necessary for normal recycling of cellular constituents and for appropriate …

Autophagy, signaling and obesity

VJ Lavallard, AJ Meijer, P Codogno, P Gual - Pharmacological research, 2012 - Elsevier
Autophagy is a cellular pathway crucial for development, differentiation, survival and
homeostasis. Autophagy can provide protection against aging and a number of pathologies …

Sonic hedgehog promotes autophagy of vascular smooth muscle cells

H Li, J Li, Y Li, P Singh, L Cao, L Xu… - American Journal …, 2012 - journals.physiology.org
Sonic hedgehog (Shh) is a morphogen critically involved in development that is reexpressed
in atherosclerotic lesions. It also stimulates proliferation of vascular smooth muscle cells …