Receptor activator of nuclear factor-κB ligand is a novel inducer of myocardial inflammation

S Ock, J Ahn, SH Lee, H Park, JW Son… - Cardiovascular …, 2012 - academic.oup.com
Aims Although increased levels of myocardial receptor activator of nuclear factor (NF)-κB
ligand (RANKL) have been reported in heart failure, the role of this pathway in mediating …

[图书][B] The renin-angiotensin system: comparative aspects

H Kobayashi, Y Takei - 2012 - books.google.com
The renin-angiotensin system and the mechanisms regulating this system developed during
the adaptive evolution of verte brates, along with many other systems involved in the in …

AVE0991, a nonpeptide compound, attenuates angiotensin II‐induced vascular smooth muscle cell proliferation via induction of heme oxygenase‐1 and …

C Sheng-Long, W Yan-Xin, H Yi-Yi… - International journal …, 2012 - Wiley Online Library
The nonpeptide AVE0991 is an agonist of the angiotensin‐(1–7)(Ang‐(1–7)) Mas receptor
and is expected to be a putative new drug for treatment of cardiovascular disease. However …

Tissue specific localization of angiotensin-(1–7) and its receptor Mas in the uterus of ovariectomized rats

J Vaz-Silva, RL Tavares, MC Ferreira… - Journal of molecular …, 2012 - Springer
The vasoactive peptide angiotensin (Ang)-(1–7) has vasodilator, antifibrotic and
antihypertrophic properties, but little is known about its regulation in the uterus. The aim of …

C-Met receptor regulation by angiotensin IV (AT4) receptor ligands

JW Harding, JW Wright, PD Elias… - US Patent …, 2012 - Google Patents
2008-06-10 Assigned to WASHINGTON STATE UNIVERSITY reassignment WASHINGTON
STATE UNIVERSITY ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

[图书][B] Cardiac Adaptation in Heart Failure: Risks due to myocardial phenotype changes

J Holtz, H Drexler, H Just - 2012 - books.google.com
Traditionally, cardiac hypertrophy is regarded as an adaptation of the heart to permanent
mechanical overload. Regardless of the fact that many different and often unknown primary …

Renin-angiotensin-aldosterone system genes and the complex hypertrophic phenotype of hypertrophic cardiomyopathy

N Carstens - 2012 - scholar.sun.ac.za
Left ventricular hypertrophy (LVH) is a strong independent predictor of cardiovascular
morbidity and mortality, while its regression is associated with an improved clinical …

Survivin Gene Therapy Using Ultrasound-Targeted Microbubble Destruction in a Rat Model of Doxorubicin-Induced Cardiomyopathy

PJH Lee - 2012 - library-archives.canada.ca
With the recent advent of gene therapy, anti-apoptotic therapy has been receiving spotlight
as a potential modality to inhibit the deterioration of pump function in the failing heart. We …

[图书][B] Beta-adrenergic blockade via atenolol and its effects on blood pressure, heart rate, and renal morphology in the developing chicken Gallus gallus domesticus

JJR Lopez - 2012 - search.proquest.com
Chicken embryos were chronically exposed to the β1-blocker atenolol during one of three
stages: mesonephros (E7-E9), mesonephros-metanephros (E11-E13), or metanephros (E15 …

Терапевтическое значение и потенциальные преимущества прямых ингибиторов ренина в лечении пациентов с артериальной гипертензией

ВА Визир, АЕ Березин - Артериальная гипертензия, 2012 - cyberleninka.ru
Обзор посвящен обсуждению потенциальных преимуществ прямых ингибиторов
ренина у пациентов с артериальной гипертензией. Рассматриваются перспективы …