Clinically isolated syndrome (CIS) is a term that describes a first clinical episode with
features suggestive of multiple sclerosis (MS). It usually occurs in young adults and affects …

Neurodegeneration is the correlate of disease progression in multiple sclerosis (MS) and
thus biological biomarkers that sensitively reflect this process are much needed …

Objectives The aim of the present study was to identify proteins in cerebrospinal fluid (CSF)
with different abundance between patients with relapsing‐remitting multiple sclerosis …

Background: Chitinase 3-like 1 (CHI3L1) is upregulated in a wide variety of inflammatory
conditions. Recent studies have pointed to a role of CHI3L1 in multiple sclerosis (MS) …

We previously reported that YKL-40, the human analog of mouse breast regression protein
39 ([BRP-39] chitinase 3-like 1), is elevated in the cerebrospinal fluid of patients with a …

Clinically relevant formalin-fixed and paraffin-embedded (FFPE) tissues have not been
widely used in neuroproteomic studies because many proteins are presumed to be …

Objective: To use a new, unbiased biomarker discovery strategy to obtain and assess
proteomic data from cerebrospinal fluid (CSF) of patients with multiple sclerosis (MS) …

Multiple sclerosis is a disabling inflammatory and neurodegenerative disorder that
predominantly affects young adults. There is a great need for biomarkers, which could …

Calponin-3 is an actin-interacting protein and is expressed in the brain. Our previous
microarray scan has found an up-regulation of calponin-3 gene CNN3 in the temporal lobe …

This is a comment on" Implication of perturbed axoglial apparatus in early pediatric multiple
sclerosis." Ann Neurol. 2012 May; 71 (5): 601-13. This is a comment on" Proteomic pattern …