The development of the human kidney is a complex process that requires interactions
between epithelial and mesenchymal cells, eventually leading to the coordinated growth …

The mammalian kidney, which at maturity contains thousands of nephrons joined to a highly
branched collecting duct (CD) system, is an important model system for studying the …

The identity of niche signals necessary to maintain embryonic nephron progenitors is
unclear. Here we provide evidence that Fgf20 and Fgf9, expressed in the niche, and Fgf9 …

Disruptions in the regulatory pathways controlling sex determination and differentiation can
cause disorders of sex development, often compromising reproductive function. Although …

Lengthy developmental programs generate cell diversity within an organotypic framework,
enabling the later physiological actions of each organ system. Cell identity, cell diversity and …

Relative positions of neurons within mature murine pelvic ganglia based on expression of
neurotransmitters have been described. However the spatial organization of developing …

Abstract The Genitourinary Development Molecular Atlas Project (GUDMAP) aims to
document gene expression across time and space in the developing urogenital system of …

Studies into the molecular basis of morphogenesis frequently begin with investigations into
gene expression across time and cell type in that organ. One of the most anatomically …

The science of maintaining tissues and cells from higher animals in culture is almost exactly
a century old. Ross Harrison, in his classic 1910 paper1, cultured neural tubes and …