Concentration‐dependent mechanisms of cell penetration and killing by the de novo designed antifungal hexapeptide PAF26

A Muñoz, JF Marcos, ND Read - Molecular Microbiology, 2012 - Wiley Online Library
Recent evidence indicates that antimicrobial peptides can kill microbes in more complex
ways than just by membrane permeabilization. In this study, the mechanism of …

Antimicrobial peptides for plant disease control. From discovery to application

E Montesinos, E Badosa, J Cabrefiga… - … wonders: Peptides for …, 2012 - ACS Publications
Sustainable protection of plant crops against diseases relies on a rational use of pesticides
and to a reduction of the number of active ingredients to the more selective, less toxic and …

Antimicrobial peptides as a promising alternative for plant disease protection

B López-García, B San Segundo… - Small wonders: peptides …, 2012 - ACS Publications
Plants produce antimicrobial peptides (AMPs) to defend themselves against pathogens. The
repertoire of AMPs synthesized by plants is extremely large, with hundreds of different AMPs …

Antifungal Activity of (KW)n or (RW)n Peptide against Fusarium solani and Fusarium oxysporum

R Gopal, H Na, CH Seo, Y Park - International Journal of Molecular …, 2012 - mdpi.com
The presence of lysine (Lys) or arginine (Arg) and tryptophan (Trp) are important for the
antimicrobial effects of cationic peptides. Therefore, we designed and synthesized a series …

Sensitivity of Saccharomyces cerevisiae to the cell-penetrating antifungal peptide PAF26 correlates with endogenous nitric oxide (NO) production

L Carmona, M Gandía, B López-García… - … and Biophysical Research …, 2012 - Elsevier
PAF26 is a synthetic fungicidal hexapeptide with cell-penetration properties and non-lytic
mode of action. We demonstrate herein the endogenous accumulation of reactive oxygen …

Direct cell penetration of the antifungal peptide, MMGP1, in Candida albicans

M Pushpanathan, J Rajendhran… - Journal of Peptide …, 2012 - Wiley Online Library
An antifungal peptide, MMGP1, was recently identified from marine metagenome. The
mechanism of cellular internalization of this peptide in Candida albicans was studied using …

Antifungal peptides: exploiting non-lytic mechanisms and cell penetration properties

JF Marcos, M Gandía, E Harries… - … wonders: peptides for …, 2012 - ACS Publications
Antimicrobial peptides with antifungal activity have not received as much consideration as
their antibacterial counterparts, which is probably a consequence of the higher impact of …

Activity of naturally derived antimicrobial peptides against filamentous fungi relevant for agriculture

P Larrañaga, P Díaz-Dellavalle… - Sustainable …, 2012 - open.journal4submit.com
The search for environmentally biocompatible and cost-effective methods to control
filamentous fungi in agriculture is becoming increasingly urgent. In vitro antimicrobial activity …

Antimicrobial peptides

JF Marcos, P Manzanares - … ; John Wiley & Sons: Hoboken, NJ …, 2012 - Wiley Online Library
Antimicrobial peptides Page 204 CHAPTER 8 ANTIMICROBIAL PEPTIDES JOSE F. MARCOS1
and PALOMA MANZANARES2 1 Departamento de Ciencia de los Alimentos, Consejo …

Live-cell imaging and analysis shed light on the complexity and dynamics of antimicrobial peptide action

A Muñoz, ND Read - Frontiers in Immunology, 2012 - frontiersin.org
Mochon and Liu, 2008; Jang et al., 2010; Mania et al., 2010; Srinivas et al., 2010). The
fluorescent AMPs commonly retain their antifungal activity although this may be reduced …