Airway diseases are highly prevalent worldwide; however, the prevalence of these diseases
is underestimated. Although these diseases present several common characteristics, they …

Significant cardiac morbidity and mortality exists in patients with COPD. Shared risk factors
include age, smoking history and exposure to air pollution and passive smoke. Although the …

BACKGROUND: According to the GOLD international guidelines, the treatment of chronic
obstructive pulmonary disease (COPD) should be proportional to the severity of airflow …

The role of small airway abnormalities in asthma pathogenesis has been extensively studied
and debated for several decades. However, whether or not small airway abnormalities play …

This article focuses on recent data which highlight the clinical settings in which exhaled nitric
oxide (FE NO) is potentially helpful, or not, as a clinical tool. It is becoming clearer that …

Methacholine challenge testing is a valuable diagnostic and research tool used by clinicians
to assist in the diagnosis of asthma, and by researchers to understand disease …

Severe asthma affects fewer than 10% of patients with asthma, is associated with a severe
risk of death and disability, has a great impact on health and quality of life, and represents a …

Susceptibility to infections with gram-positive bacteria, which are an important trigger of
exacerbations, is increased in COPD and asthma. Unraveling the underlying mechanisms …

Asthma and chronic obstructive pulmonary disease (COPD) are the two most prominent
chronic inflammatory lung diseases with increasing prevalence. Both diseases are …

The EvA study is a European Union-funded project under the Seventh Framework
Programme (FP7), which aims at defining new markers for chronic obstructive pulmonary …