Anti-HIV nucleoside drugs: A retrospective view into the future
MK Kukhanova - Molecular biology, 2012 - Springer
The review considers the design of antiretroviral drugs based on nucleoside analogs.
Approximately 30 drugs have been approved for treating HIV-infected patients over the past …
Approximately 30 drugs have been approved for treating HIV-infected patients over the past …
Sorafenib-induced mitochondrial complex I inactivation and cell death in human neuroblastoma cells
VH Bull, K Rajalingam, B Thiede - Journal of proteome research, 2012 - ACS Publications
Sorafenib is a multikinase inhibitor that is approved for use against renal cell and
hepatocellular carcinoma. We found that sorafenib potently induced cell death in human …
hepatocellular carcinoma. We found that sorafenib potently induced cell death in human …
Qualitative serum organic acid profiles of HIV-infected individuals not on antiretroviral treatment
A Williams, G Koekemoer, Z Lindeque, C Reinecke… - Metabolomics, 2012 - Springer
The first application of gas chromatography mass spectrometry (GC–MS) metabolomics to
the analysis of organic acid profiles in sera of asymptomatic human immunodeficiency virus …
the analysis of organic acid profiles in sera of asymptomatic human immunodeficiency virus …
[HTML][HTML] Essential role of Drosophila black-pearl is mediated by its effects on mitochondrial respiration
S Roy, MK Short, ER Stanley, PT Jubinsky - The FASEB Journal, 2012 - ncbi.nlm.nih.gov
Black-pearl (Blp) is a highly conserved, essential inner-mitochondrial membrane protein.
The yeast Blp homologue, Magmas/Pam16, is required for mitochondrial protein transport …
The yeast Blp homologue, Magmas/Pam16, is required for mitochondrial protein transport …
Анти-ВИЧ нуклеозидные препараты: история создания и взгляд в будущее
МК Куханова - Молекулярная биология, 2012 - elibrary.ru
В обзоре рассматриваются данные по созданию анти-ВИЧ препаратов на основе
нуклеозидных аналогов. За 25 лет для лечения ВИЧ-инфицированных пациентов …
нуклеозидных аналогов. За 25 лет для лечения ВИЧ-инфицированных пациентов …
[HTML][HTML] Epigenetic regulation of developmental expression of Cyp2d genes in mouse liver
Y Li, X Zhong - Acta Pharmaceutica Sinica B, 2012 - Elsevier
CYP2D6 expression in liver is age-dependent. Because epigenetic mechanisms, such as
DNA methylation and histone modifications, modulate age-related gene expression during …
DNA methylation and histone modifications, modulate age-related gene expression during …
[图书][B] Metabonomics profile and corresponding immune parameters of HIV infected individuals
AA Williams - 2012 - search.proquest.com
Background: Immunological events due to infection by the human immunodeficiency virus
(HIV) perturb mitochondrial function which augments virus-induced metabolic imbalances …
(HIV) perturb mitochondrial function which augments virus-induced metabolic imbalances …