Multifarious roles of sialic acids in immunity
Sialic acids are a diverse family of monosaccharides widely expressed on all cell surfaces of
vertebrates and so‐called “higher” invertebrates, and on certain bacteria that interact with …
vertebrates and so‐called “higher” invertebrates, and on certain bacteria that interact with …
The cellular and molecular basis for malaria parasite invasion of the human red blood cell
Malaria is a major disease of humans caused by protozoan parasites from the genus
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …
Erythrocyte and reticulocyte binding-like proteins of Plasmodium falciparum
The global agenda for malaria eradication would benefit from development of a highly
efficacious vaccine that protects against disease and interrupts transmission of Plasmodium …
efficacious vaccine that protects against disease and interrupts transmission of Plasmodium …
Defining the Antigenic Diversity of Plasmodium falciparum Apical Membrane Antigen 1 and the Requirements for a Multi-Allele Vaccine against Malaria
Apical Membrane Antigen 1 (AMA1) is a leading malaria vaccine candidate and a target of
naturally-acquired human immunity. Plasmodium falciparum AMA1 is polymorphic and in …
naturally-acquired human immunity. Plasmodium falciparum AMA1 is polymorphic and in …
Passive immunoprotection of Plasmodium falciparum-infected mice designates the CyRPA as candidate malaria vaccine antigen
AM Dreyer, H Matile, P Papastogiannidis… - The Journal of …, 2012 - journals.aai.org
An effective malaria vaccine could prove to be the most cost-effective and efficacious means
of preventing severe disease and death from malaria. In an endeavor to identify novel …
of preventing severe disease and death from malaria. In an endeavor to identify novel …
High Affinity Antibodies to Plasmodium falciparum Merozoite Antigens Are Associated with Protection from Malaria
Background Malaria kills almost 1 million people every year, but the mechanisms behind
protective immunity against the disease are still largely unknown. Methodology/Principal …
protective immunity against the disease are still largely unknown. Methodology/Principal …
The Plasmodium falciparum Erythrocyte Invasion Ligand Pfrh4 as a Target of Functional and Protective Human Antibodies against Malaria
Background Acquired antibodies are important in human immunity to malaria, but key
targets remain largely unknown. Plasmodium falciparum reticulocyte-binding-homologue-4 …
targets remain largely unknown. Plasmodium falciparum reticulocyte-binding-homologue-4 …
Opsonization of malaria-infected erythrocytes activates the inflammasome and enhances inflammatory cytokine secretion by human macrophages
J Zhou, LE Ludlow, W Hasang, SJ Rogerson… - Malaria Journal, 2012 - Springer
Abstract Background Antibody opsonization of Plasmodium falciparum-infected erythrocytes
(IE) plays a crucial role in anti-malarial immunity by promoting clearance of blood-stage …
(IE) plays a crucial role in anti-malarial immunity by promoting clearance of blood-stage …
Lack of evidence from studies of soluble protein fragments that Knops blood group polymorphisms in complement receptor-type 1 are driven by malaria
PB Tetteh-Quarcoo, CQ Schmidt, WH Tham, R Hauhart… - PloS one, 2012 - journals.plos.org
Complement receptor-type 1 (CR1, CD35) is the immune-adherence receptor, a
complement regulator, and an erythroid receptor for Plasmodium falciparum during …
complement regulator, and an erythroid receptor for Plasmodium falciparum during …
Nuclear repositioning precedes promoter accessibility and is linked to the switching frequency of a Plasmodium falciparum invasion gene
BI Coleman, U Ribacke, M Manary, AK Bei… - Cell host & …, 2012 - cell.com
Variation of surface adhesins, such as the Plasmodium falciparum erythrocyte invasion
ligand PfRh4, is critical for virulence and immune evasion in many microbes. While …
ligand PfRh4, is critical for virulence and immune evasion in many microbes. While …