[HTML][HTML] Recent advances in non-small cell lung cancer biology and clinical management
P Saintigny, JA Burger - Discovery medicine, 2012 - discoverymedicine.com
Despite advances in surgery, chemotherapy, and radiotherapy over the last decades, the
death rate from lung cancer has remained largely unchanged, which is mainly due to …
death rate from lung cancer has remained largely unchanged, which is mainly due to …
G protein‐coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function
A Tadevosyan, G Vaniotis, BG Allen… - The Journal of …, 2012 - Wiley Online Library
G protein‐coupled receptors (GPCRs) play key physiological roles in numerous tissues,
including the heart, and their dysfunction influences a wide range of cardiovascular …
including the heart, and their dysfunction influences a wide range of cardiovascular …
[HTML][HTML] In vitro and in vivo therapeutic efficacy of CXCR4 antagonist BKT140 against human non–small cell lung cancer
D Fahham, ID Weiss, M Abraham, K Beider… - The Journal of thoracic …, 2012 - Elsevier
OBJECTIVES: CXCR4/CXCL12 interactions promote non–small cell lung cancer (NSCLC)
growth and dissemination. Furthermore, this axis might promote NSCLC resistance to …
growth and dissemination. Furthermore, this axis might promote NSCLC resistance to …
CXCR4/CXCL12 expression profile is associated with tumor microenvironment and clinical outcome of liver metastases of colorectal cancer
N Sakai, H Yoshidome, T Shida, F Kimura… - Clinical & experimental …, 2012 - Springer
Interaction between CXCR4 and CXCL12 plays a role in tumor progression. The present
study examined CXCR4, CXCL12 and CD133 expression in liver metastases of colorectal …
study examined CXCR4, CXCL12 and CD133 expression in liver metastases of colorectal …
Prognostic value of the chemokine receptor CXCR4 and epithelial-to-mesenchymal transition in patients with squamous cell carcinoma of the mobile tongue
S Albert, M Hourseau, C Halimi, M Serova… - Oral oncology, 2012 - Elsevier
Objective The aim of this study was to evaluate the expression and the prognostic value of
chemokine receptor 4 (CXCR4), its cognate ligand the CXCL12, and markers of epithelial-to …
chemokine receptor 4 (CXCR4), its cognate ligand the CXCL12, and markers of epithelial-to …
Differential transcriptomic analysis of spontaneous lung tumors in b6c3f1 mice: Comparison to human non–small cell lung cancer
AR Pandiri, RC Sills, V Ziglioli, TVT Ton… - Toxicologic …, 2012 - journals.sagepub.com
Lung cancer is the leading cause of cancer-related death in people and is mainly due to
environmental factors such as smoking and radon. The National Toxicology Program (NTP) …
environmental factors such as smoking and radon. The National Toxicology Program (NTP) …
The expression of the hypoxia markers CA9 and CXCR4 is correlated with survival in patients with neuroendocrine tumours of the ileum
Abstract Background/Aim: The hypoxia-inducible factor pathway regulates the expression of
a diverse group of molecules such as CA9 and CXCR4. Our aim was to investigate the …
a diverse group of molecules such as CA9 and CXCR4. Our aim was to investigate the …
过表达SDF-1a 帕金森病小鼠模型的建立与评价
邹志浩， 张文德， 魏成， 吴勤奋， 张世忠， 王媛媛 - 新疆医学, 2012 - cqvip.com
目的: 探讨建立及评价稳定的脑内过表达基质细胞衍生因子-1a (str-) malcellderivedfae—tor—l,
SDF—la) 的帕金森病(Parkinsongdisease, PD) 小鼠模型的方法. 方法: 采用间隔多次注射方法 …
SDF—la) 的帕金森病(Parkinsongdisease, PD) 小鼠模型的方法. 方法: 采用间隔多次注射方法 …
Differential expression of CXCR4 in conventional high-grade and low-grade central osteosarcoma and its prognostic implications
HR Park, JW Seo, P Bacchini, F Bertoni… - The Journal of the …, 2012 - koreascience.kr
Purpose: The chemokine receptor CXCR4 has been reported to be aberrantly expressed in
human cancer and has been shown to participate in cancer metastasis. We compared the …
human cancer and has been shown to participate in cancer metastasis. We compared the …
Chemokines & Their Receptors in Non-Small Cell Lung Cancer Detection
One of the most commonly diagnosed cancers is non-small cell lung cancer (NSCLC), which
is the leading cause of lung cancer related deaths throughout the world 1; 2. NSCLC is an …
is the leading cause of lung cancer related deaths throughout the world 1; 2. NSCLC is an …