Regulation of nonsense‐mediated mRNA decay
L Huang, MF Wilkinson - Wiley Interdisciplinary Reviews: RNA, 2012 - Wiley Online Library
Nonsense‐mediated mRNA decay (NMD) is a highly conserved pathway that was originally
identified as a RNA surveillance mechanism that degrades aberrant mRNAs harboring …
identified as a RNA surveillance mechanism that degrades aberrant mRNAs harboring …
[HTML][HTML] Rescue of nonsense mutations by amlexanox in human cells
S Gonzalez-Hilarion, T Beghyn, J Jia… - Orphanet journal of rare …, 2012 - Springer
Background Nonsense mutations are at the origin of many cancers and inherited genetic
diseases. The consequence of nonsense mutations is often the absence of mutant gene …
diseases. The consequence of nonsense mutations is often the absence of mutant gene …
Transcriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability
LS Nguyen, L Jolly, C Shoubridge, WK Chan… - Molecular …, 2012 - nature.com
The nonsense-mediated mRNA decay (NMD) pathway was originally discovered by virtue of
its ability to rapidly degrade aberrant mRNAs with premature termination codons. More …
its ability to rapidly degrade aberrant mRNAs with premature termination codons. More …
Analysis of nonsense‐mediated mRNA decay in mammalian cells
P Nicholson, R Joncourt… - Current Protocols in Cell …, 2012 - Wiley Online Library
The nonsense‐mediated mRNA decay (NMD) pathway acts to selectively identify and
degrade mRNAs that contain a premature translation termination codon (PTC), and hence …
degrade mRNAs that contain a premature translation termination codon (PTC), and hence …