[HTML][HTML] The global pipeline of new medicines for the control and elimination of malaria
MP Anthony, JN Burrows, S Duparc, J JMoehrle… - Malaria journal, 2012 - Springer
Over the past decade, there has been a transformation in the portfolio of medicines to
combat malaria. New fixed-dose artemisinin combination therapy is available, with four …
combat malaria. New fixed-dose artemisinin combination therapy is available, with four …
Biowaiver monographs for immediate release solid oral dosage forms: amodiaquine hydrochloride
A Nair, B Abrahamsson, DM Barends, DW Groot… - Journal of …, 2012 - Elsevier
The present monograph reviews data relevant to applying the biowaiver procedure for the
approval of immediate release (IR) multisource solid dosage forms containing amodiaquine …
approval of immediate release (IR) multisource solid dosage forms containing amodiaquine …
[HTML][HTML] Therapeutic efficacy of artemether-lumefantrine combination in the treatment of uncomplicated malaria among children under five years of age in three …
Abstract Background In 2008, artemether-lumefantrine (AL) and dihydroartemisinin-
piperaquine (DHAP) were added to artesunate-amodiaquine (AS-AQ) as first-line drugs for …
piperaquine (DHAP) were added to artesunate-amodiaquine (AS-AQ) as first-line drugs for …
[HTML][HTML] Repeated artemisinin-based combination therapies in a malaria hyperendemic area of Mali: efficacy, safety, and public health impact
I Sagara, B Fofana, J Gaudart, B Sidibe… - The American journal …, 2012 - ncbi.nlm.nih.gov
Artemisinin-based combination therapies (ACTs) are the first-line treatment of
uncomplicated malaria. The public health benefit and safety of repeated administration of a …
uncomplicated malaria. The public health benefit and safety of repeated administration of a …
Antimalarial efficacy of a quantified extract of Nauclea pobeguinii stem bark in human adult volunteers with diagnosed uncomplicated falciparum malaria. Part 2: a …
K Mesia, L Tona, MM Mampunza… - Planta …, 2012 - thieme-connect.com
According to the promising results of the Phase I and Phase IIA clinical trials with the herbal
medicinal product PR 259 CT1 consisting of an 80% ethanolic extract of the stem bark of …
medicinal product PR 259 CT1 consisting of an 80% ethanolic extract of the stem bark of …
[HTML][HTML] Therapy of uncomplicated falciparum malaria in Europe: MALTHER–a prospective observational multicentre study
O Bouchaud, N Mühlberger, P Parola, G Calleri… - Malaria journal, 2012 - Springer
Background Malaria continues to be amongst the most frequent infectious diseases
imported to Europe. Whilst European treatment guidelines are based on data from studies …
imported to Europe. Whilst European treatment guidelines are based on data from studies …
M alaria intervention policies and pharmaceutical nanotechnology as a potential tool for malaria management
N Kuntworbe, N Martini, J Shaw… - Drug Development …, 2012 - Wiley Online Library
Abstract Strategy, Management and Health Policy Enabling Technology, Genomics,
Proteomics Preclinical Research Preclinical Development Toxicology, Formulation Drug …
Proteomics Preclinical Research Preclinical Development Toxicology, Formulation Drug …
[HTML][HTML] Comparing changes in haematologic parameters occurring in patients included in randomized controlled trials of artesunate-amodiaquine vs single and …
Abstract Background Artesunate-amodiaquine (AS&AQ) is a widely used artemisinin
combination therapy (ACT) for falciparum malaria. A comprehensive appreciation of its …
combination therapy (ACT) for falciparum malaria. A comprehensive appreciation of its …
[HTML][HTML] Electrocardiographic study in Ghanaian children with uncomplicated malaria, treated with artesunate-amodiaquine or artemether-lumefantrine
GO Adjei, C Oduro-Boatey, OP Rodrigues… - Malaria journal, 2012 - Springer
Background Several anti-malarial drugs are associated with adverse cardiovascular effects.
These effects may be exacerbated when different anti-malarials are used in combination …
These effects may be exacerbated when different anti-malarials are used in combination …
[HTML][HTML] Multicentre study evaluating the non-inferiority of the new paediatric formulation of artesunate/amodiaquine versus artemether/lumefantrine for the …
B Faye, T Kuété, CP Kiki-Barro, RC Tine, T Nkoa… - Malaria Journal, 2012 - Springer
Background This multicentre study was carried out in Cameroon, Ivory Coast and Senegal to
evaluate the non-inferiority of the new paediatric formulation of artesunate/amodiaquine …
evaluate the non-inferiority of the new paediatric formulation of artesunate/amodiaquine …