A novel, externally validated inflammation-based prognostic algorithm in hepatocellular carcinoma: the prognostic nutritional index (PNI)

DJ Pinato, BV North, R Sharma - British journal of cancer, 2012 - nature.com
Background: There is increasing evidence that the presence of an ongoing systemic
inflammatory response is a stage-independent predictor of poor outcome in patients with …

Cardiac glycosides exert anticancer effects by inducing immunogenic cell death

L Menger, E Vacchelli, S Adjemian, I Martins… - Science translational …, 2012 - science.org
Some successful chemotherapeutics, notably anthracyclines and oxaliplatin, induce a type
of cell stress and death that is immunogenic, hence converting the patient's dying cancer …

Human immunodeficiency virus‐associated plasmablastic lymphoma: poor prognosis in the era of highly active antiretroviral therapy

JJ Castillo, M Furman, BE Beltrán, M Bibas, M Bower… - Cancer, 2012 - Wiley Online Library
BACKGROUND: Plasmablastic lymphoma (PBL) is a rare and aggressive B‐cell lymphoma
strongly associated with human immunodeficiency virus (HIV) infection. The authors …

Interleukin-7 and immune reconstitution in cancer patients: a new paradigm for dramatically increasing overall survival

M Morre, S Beq - Targeted oncology, 2012 - Springer
Although great effort is being expended in the development of cancer immunotherapies, it is
surprising that global lymphopenia and its various dimensions are not being systematically …

Blood lymphocyte-to-monocyte ratio identifies high-risk patients in diffuse large B-cell lymphoma treated with R-CHOP

ZM Li, JJ Huang, Y Xia, J Sun, Y Huang, Y Wang… - PloS one, 2012 - journals.plos.org
Background Recent research has shown a correlation between immune microenvironment
and lymphoma biology. This study aims to investigate the prognostic significance of the …

[HTML][HTML] Advanced well-differentiated/dedifferentiated liposarcomas: role of chemotherapy and survival

A Italiano, M Toulmonde, A Cioffi, N Penel, N Isambert… - Annals of …, 2012 - Elsevier
Background Data regarding the role of systemic therapy in patients with advanced well-
differentiated/dedifferentiated liposarcomas (WDLPS/DDLPS) are limited. Methods From …

Absolute lymphocyte count is associated with survival in ovarian cancer independent of tumor-infiltrating lymphocytes

K Milne, C Alexander, JR Webb, W Sun… - Journal of Translational …, 2012 - Springer
Background The immune system strongly influences outcome in patients with ovarian
cancer. In particular, the absolute lymphocyte count in peripheral blood (ALC) and the …

Lymphopenia combined with low TCR diversity (divpenia) predicts poor overall survival in metastatic breast cancer patients

M Manuel, O Trédan, T Bachelot, G Clapisson… - …, 2012 - Taylor & Francis
Lymphopenia (< 1Giga/L) detected before initiation of chemotherapy is a predictive factor for
death in metastatic solid tumors. Combinatorial T cell repertoire (TCR) diversity was …

Relationship between lymphocytopenia and circulating tumor cells as prognostic factors for overall survival in metastatic breast cancer

U De Giorgi, M Mego, E Scarpi, M Giuliano… - Clinical breast …, 2012 - Elsevier
Introduction Lymphocytopenia and circulating tumor cells (CTCs) have been reported as
independent prognostic factors for overall survival (OS) in metastatic breast cancer (MBC) …

Elevated neutrophil to lymphocyte ratio predicts poor prognosis in advanced colorectal cancer patients receiving oxaliplatin-based chemotherapy

M Kaneko, H Nozawa, K Sasaki, K Hongo, M Hiyoshi… - Oncology, 2012 - karger.com
Background: The aim of this study was to assess whether the neutrophil to lymphocyte ratio
(NLR) and other laboratory markers may predict the prognosis of advanced colorectal …