In medical contexts, the word “phenotype” is used to refer to some deviation from normal
morphology, physiology, or behavior. The analysis of phenotype plays a key role in clinical …

Psoriasis is a systemic, immune‐mediated disorder, characterized by inflammatory skin and
joint manifestations. A range of co‐morbidities is associated with psoriasis, including …

Increasing epidemiological evidence suggests independent associations between psoriasis
and cardiovascular and metabolic disease. Our objective was to test the hypothesis that …

Psoriasis is a common inflammatory disorder of the skin and other organs. We have
determined that mutations in CARD14, encoding a nuclear factor of kappa light chain …

Psoriasis is a complex disease with an expanding definition of its pathological features. We
sought to expand/refine the psoriasis transcriptome using 85 paired lesional and non …

The cause of psoriasis, a common chronic inflammatory skin disease, is not fully understood.
Microarray experiments have been widely used in recent years to identify genes associated …

Objectives Both overall and central obesity have been associated with the risk of psoriasis in
a prospective study. Data on the association between obesity and psoriatic arthritis (PsA) …

Psoriasis, a chronic inflammatory skin disease, has been linked to increased myocardial
infarction and stroke. Functional impairment of HDL may contribute to the excess …

Lipin-2 is a member of the lipin family of enzymes, which are key effectors in the
biosynthesis of lipids. Mutations in the human lipin-2 gene are associated with inflammatory …

Psoriasis vulgaris is a chronic, debilitating skin disease that affects millions of people
worldwide. There is no mouse model that accurately reproduces all facets of the disease, but …