Two-Drug Antimicrobial Chemotherapy: A Mathematical Model and Experiments with Mycobacterium marinum
P Ankomah, BR Levin - PLoS pathogens, 2012 - journals.plos.org
Multi-drug therapy is the standard-of-care treatment for tuberculosis. Despite this, virtually all
studies of the pharmacodynamics (PD) of mycobacterial drugs employed for the design of …
studies of the pharmacodynamics (PD) of mycobacterial drugs employed for the design of …
Antinociceptive effects of tramadol in co-administration with metamizol after single and repeated administrations in rats
LA Moreno-Rocha, AM Domínguez-Ramírez… - Pharmacology …, 2012 - Elsevier
Combinations of two analgesic drugs of the same or different class are widely used in
clinical therapy to enhance its antinociceptive effects and reduce the side effects. In order to …
clinical therapy to enhance its antinociceptive effects and reduce the side effects. In order to …
Synergistic antinociceptive actions and tolerance development produced by morphine–fentanyl coadministration: Correlation with μ-opioid receptor internalization
A Silva-Moreno, C Gonzalez-Espinosa… - European journal of …, 2012 - Elsevier
It has been described that coadministration of opioids with low doses of other analgesics
can reduce adverse effects and increase antinociception, but combinations of two μ-opioid …
can reduce adverse effects and increase antinociception, but combinations of two μ-opioid …
The role of cyclo-oxygenase inhibitors in attenuating opioid-induced tolerance, hyperalgesia, and dependence
E Akbari - Medical Hypotheses, 2012 - Elsevier
There is no denying that opioids are the most important analgesic drugs which are widely
used in clinical situations. Still, prolonged administration of these drugs can cause to reduce …
used in clinical situations. Still, prolonged administration of these drugs can cause to reduce …
Tolerance to anti-nociceptive effects of sodium-salicylate and morphine decreases adenosine deaminase activity in the rat hippocampus.
Introduction: Adenosine has been considered as a fine-tuner of the neurotransmitters in the
nerve system. Adaptive changes in the brain adenosine system occur in some patho …
nerve system. Adaptive changes in the brain adenosine system occur in some patho …