Curcumin: a novel Stat3 pathway inhibitor for chemoprevention of lung cancer

MG Alexandrow, LJ Song, S Altiok, J Gray… - European Journal of …, 2012 - journals.lww.com
Multiple studies from independent groups find evidence for signal transducer and activator
of transcription 3 (Stat3) activation in nearly 50% of lung cancers, suggesting a functional …

Nicotine induces inhibitor of differentiation-1 in a Src-dependent pathway promoting metastasis and chemoresistance in pancreatic adenocarcinoma

JG Trevino, S Pillai, S Kunigal, S Singh, WJ Fulp… - Neoplasia, 2012 - Elsevier
Smoking is a significant risk factor for pancreatic cancer, but the molecular mechanisms by
which tobacco smoke components promote the growth and progression of these cancers are …

[HTML][HTML] Elevated expression of Fn14 in non-small cell lung cancer correlates with activated EGFR and promotes tumor cell migration and invasion

TG Whitsett, E Cheng, L Inge, K Asrani… - The American journal of …, 2012 - Elsevier
Lung cancer is the leading cause of cancer deaths worldwide; approximately 85% of these
cancers are non-small cell lung cancer (NSCLC). Patients with NSCLC frequently have …

Nicotine-mediated induction of E-selectin in aortic endothelial cells requires Src kinase and E2F1 transcriptional activity

V Alamanda, S Singh, NJ Lawrence… - … and biophysical research …, 2012 - Elsevier
Smoking is highly correlated with enhanced likelihood of atherosclerosis by inducing
endothelial dysfunction. In endothelial cells, various cell-adhesion molecules including E …

p120-catenin modulates airway epithelial cell migration induced by cigarette smoke

L Zhang, M Gallup, L Zlock, W Finkbeiner… - Biochemical and …, 2012 - Elsevier
Cigarette smoking has been linked to almost all major types of cancer. Emerging evidence
suggests that smoking initiates transformed cell growth and migration by disrupting cell–cell …

Matrix Metalloproteinase genes are transcriptionally regulated by E2F transcription factors: a link between cell cycle control and metastatic progression

JL Johnson - 2012 - digitalcommons.usf.edu
Abstract The RbµE2F transcriptional regulatory pathway plays a critical role in the cell cycle.
Rb is inactivated through multiple waves of phosphorylation, mediated mainly by cyclin D …

Distinct transcriptional signatures of aneuploidy in murine pluripotent cell populations

S Skylaki - 2012 - era.ed.ac.uk
Genomic integrity in mouse embryonic and induced pluripotent stem cells can be
compromised by factors such as extended time in culture and cellular reprogramming …

[PDF][PDF] Transforming growth factor β superfamily signaling and its role in B-cell lymphoma.

M Bakkebø - 2012 - duo.uio.no
The immune system has developed to protect the host against pathogens like bacteria,
viruses and parasites. It is a system comprised of both cellular and humoral components …

[引用][C] 卵巢子宫内膜样癌组织中Id1 蛋白的表达

郭晓慧, 赵彩妮, 徐菲菲, 于小玲 - 中国现代医药杂志, 2012