Male mice produced by in vitro culture have reduced fertility and transmit organomegaly and glucose intolerance to their male offspring

A Calle, A Miranda, R Fernandez-Gonzalez… - Biology of …, 2012 - academic.oup.com
It has been reported that suboptimal in vitro culture (IVC) of mouse embryos can affect the
postnatal expression of epigenetically sensitive alleles, resulting in altered postnatal growth …

Parthenogenesis in non-rodent species: developmental competence and differentiation plasticity

TAL Brevini, G Pennarossa, A Vanelli, S Maffei… - Theriogenology, 2012 - Elsevier
An oocyte can activate its developmental process without the intervention of the male
counterpart. This form of reproduction, known as parthenogenesis, occurs spontaneously in …

[HTML][HTML] Development of retinal pigment epithelium from human parthenogenetic embryonic stem cells and microRNA signature

WB Li, YS Zhang, ZY Lu, LJ Dong… - … & visual science, 2012 - iovs.arvojournals.org
Purpose.: We investigated the potential of human parthenogenetic embryonic stem cells
(hPESCs) to differentiate into RPE cells, and identified development-regulating microRNAs …

Higher copy number variation and diverse X chromosome inactivation in parthenote-derived human embryonic stem cells

WQ Liu, LY Guo, WZ He, Q Li, XF Sun - Journal of Reproduction and …, 2012 - jstage.jst.go.jp
Parthenote-derived human embryonic stem cells (phESCs) have many advantages over
conventionally derived human embryonic stem cells (hESCs), but a more thorough …

Ectopic expression of Fgf3 leads to aberrant lineage segregation in the mouse parthenote preimplantation embryos

YH Chen, J Yu - Developmental Dynamics, 2012 - Wiley Online Library
Background: Parthenogenetic mammalian embryos were reported to die in utero no later
than the 25‐somite stage due to abnormal development of both embryonic and …

Parthenogenetic Activation-Induced Pluripotent Stem Cells and Potential Applications

Y Yin, N Liu, DL Keefe, L Liu - Stem Cells and Cancer Stem Cells, Volume …, 2012 - Springer
Parthenogenesis is the process by which an egg can develop into an embryo without
fertilization. Parthenogenesis can be induced by artificial activation of an egg in mammals …

Generation of Histocompatible Tissues via Parthenogenesis

PW Lampton, JA Newmark, AA Kiessling - The Immunological Barriers to …, 2012 - Springer
Parthenogenic stem (PS) cells are a potential source of histocompatible, pluripotent cells for
transplantation therapy that does not rely on fertilized embryos. Parthenotes result from …

Function and evolution of the piRNA pathway in the amniote gonad and human ovarian cancer.

SL Lim - 2012 - digital.library.adelaide.edu.au
The Piwi-interacting RNA (piRNA) pathway is a RNA silencing pathway which represses the
expression of gene and transposable elements (TE) in the gonads via the binding of piRNAs …

[引用][C] 2 种化学激活方法制备的小鼠孤雌胚胎早期发育指标比较研究

王英, 罗永, 尹艳云, 刘云海, 盛熙晖, 邓桂馨, 郭勇… - 中国农学通报, 2012