Insulin-like growth factor II-messenger RNA-binding protein-3 and lung cancer

JJ Findeis-Hosey, H Xu - Biotechnic & Histochemistry, 2012 - Taylor & Francis
Insulin-like growth factor II-messenger RNA-binding protein 3 (IMP3) is an oncofetal RNA-
binding protein that promotes tumor cell proliferation by enhancing IGF-II protein synthesis …

[HTML][HTML] Insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3) is a marker of unfavourable prognosis in colorectal cancer

P Lochhead, Y Imamura, T Morikawa, A Kuchiba… - European journal of …, 2012 - Elsevier
BACKGROUND: Evidence suggests that insulin-like growth factor 2 messenger RNA
binding protein 3 (IGF2BP3, also known as IMP3) represents a promising cancer biomarker …

Role of insulin‐like growth factor‐II mRNA‐binding protein‐3 in invadopodia formation and the growth of oral squamous cell carcinoma in athymic nude mice

YS Hwang, KK Park, IH Cha, J Kim, WY Chung - Head & neck, 2012 - Wiley Online Library
Background The invadopodia are specialized structures that degrade the extracellular
matrix (ECM) and promote cell invasion and metastasis. Understanding the forms and …

Functional invadopodia formation through stabilization of the PDPN transcript by IMP-3 and cancer-stromal crosstalk for PDPN expression

YS Hwang, Z Xianglan, KK Park, WY Chung - Carcinogenesis, 2012 - academic.oup.com
We previously reported that insulin-like growth factor-II mRNA-binding protein-3 (IMP-3)
depletion (IMP-3 Δ) was shown to inhibit invadopodia formation and extracellular matrix …

Oncofetal protein, IMP‐3, a potential marker for prediction of postoperative peritoneal dissemination in gastric adenocarcinoma

K Okada, Y Fujiwara, Y Nakamura… - Journal of surgical …, 2012 - Wiley Online Library
Background The aim of this study was to determine the expression of insulin‐like growth
factor‐II messenger RNA (mRNA)‐binding protein‐3 (IMP‐3) and its clinical significance in …

Significance of molecular markers in survival prediction of oral squamous cell carcinoma

KY Kim, SJ Li, JD Cha, X Zhang, IH Cha - Head & neck, 2012 - Wiley Online Library
Background An accurate system for predicting the survival of patients with oral squamous
cell carcinoma (OSCC) will be useful for deciding appropriate therapies. The prediction …

Oncofetal protein IMP3: a useful diagnostic biomarker for leiomyosarcoma

K Cornejo, M Shi, Z Jiang - Human pathology, 2012 - Elsevier
An accurate diagnosis between leiomyoma and leiomyosarcoma is essential for patient
management. IMP3 is a member of the insulin-like growth factor (IGF-II) mRNA binding …

Prognostic value of insulin‐like growth factor II mRNA binding protein 3 in patients treated with radical prostatectomy

TF Chromecki, EK Cha, K Pummer, DS Scherr… - BJU …, 2012 - Wiley Online Library
Study Type–Prognosis (case series) Level of Evidence 4 What's known on the subject? and
What does the study add? Insulin‐like growth factor II mRNA binding protein 3 (IMP3) is …

肺癌の免疫療法に有用な新規腫瘍関連抗原の同定と免疫学的解析

冨田雄介 - 2012 - kumadai.repo.nii.ac.jp
1 要旨 [目的] 肺癌は最も予後不良な癌の一つであり, 肺癌による死亡率は, 本邦において悪性腫瘍
の死亡原因の第一位である. 手術, 化学療法や放射線療法を中心とした治療が行われているが …