Leptin, adiponectin and other adipokines in gestational diabetes mellitus and pre‐eclampsia

K Miehle, H Stepan, M Fasshauer - Clinical endocrinology, 2012 - Wiley Online Library
Proteins secreted from adipocytes–so‐called adipokines–influence metabolic and vascular
function. Recent data suggest that various adipokines are dysregulated in gestational …

New insights into osteoporosis: the bone–fat connection

M Kawai, FJA de Paula… - Journal of internal …, 2012 - Wiley Online Library
Kawai M, de Paula FJA, Rosen CJ (Osaka Medical Center and Research Institute for
Maternal and Child Health, Izumi, Osaka, Japan; University of São Paulo, Ribeirão Preto …

A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism

MA Herman, OD Peroni, J Villoria, MR Schön… - Nature, 2012 - nature.com
The prevalence of obesity and type 2 diabetes is increasing worldwide and threatens to
shorten lifespan. Impaired insulin action in peripheral tissues is a major pathogenic factor …

[HTML][HTML] Clinical relevance of adipokines

M Blüher - Diabetes & metabolism journal, 2012 - synapse.koreamed.org
The incidence of obesity has increased dramatically during recent decades. Obesity
increases the risk for metabolic and cardiovascular diseases and may therefore contribute to …

Vaspin in obesity and diabetes: pathophysiological and clinical significance

M Blüher - Endocrine, 2012 - Springer
Vaspin (visceral adipose tissue-derived serpin; serpinA12) was originally identified as an
adipokine, which is predominantly secreted from visceral adipose tissue in Otsuka Long …

The multifactorial role of leptin in driving the breast cancer microenvironment

S Ando, S Catalano - Nature reviews endocrinology, 2012 - nature.com
Adipose-tissue-derived signaling molecules, including the adipokines, are emerging as key
candidate molecules that link obesity with cancer. Peritumoral, stromal, adipose tissue and …

Physiological, pathological and potential therapeutic roles of adipokines

I Falcao-Pires, P Castro-Chaves, D Miranda-Silva… - Drug discovery today, 2012 - Elsevier
Formerly regarded purely as passive energy storage, adipose tissue is now recognized as a
vital endocrine organ. Adipocytes secrete diverse peptide hormones named adipokines …

Distinct roles for specific leptin receptor signals in the development of hypothalamic feeding circuits

SG Bouret, SH Bates, S Chen, MG Myers… - Journal of …, 2012 - Soc Neuroscience
Circulating hormones influence multiple aspects of hypothalamic development and play a
role in directing formation of neural circuits. Leptin is secreted by adipocytes and functions …

[HTML][HTML] Lipophilic micronutrients and adipose tissue biology

JF Landrier, J Marcotorchino, F Tourniaire - Nutrients, 2012 - mdpi.com
Lipophilic micronutrients (LM) constitute a large family of molecules including several
vitamins (A, D, E, K) and carotenoids. Their ability to regulate gene expression is becoming …

Human obesity and endothelium‐dependent responsiveness

U Campia, M Tesauro, C Cardillo - British journal of …, 2012 - Wiley Online Library
Obesity is an ongoing worldwide epidemic. Besides being a medical condition in itself,
obesity dramatically increases the risk of development of metabolic and cardiovascular …