In recent years, prominent roles for microRNAs (miRNAs) have been uncovered in several
cardiovascular disorders. The ability to therapeutically manipulate miRNA expression and …

Background: Four distinguishing histopathological characteristics of thoracic aortic
aneurysms and dissections (TAADs) are the fragmentation or degradation of elastic fibers …

Objective—Vascular calcification significantly increases cardiovascular morbidity and
mortality. We recently reported that the deficiency of cartilage oligomeric matrix protein …

Recent research into the role of microRNA (miR) in the immune system has identified the
miR-29 family as critical regulators of key processes in adaptive immunity. The miR-29 …

Aortic aneurysms are relatively common maladies that may lead to the devastating
consequence of aortic rupture. AAAs (abdominal aortic aneurysms) and TAAs (thoracic …

Background Abdominal aortic aneurysm (AAA) is a dilatation of the aorta affecting most
frequently elderly men. Histologically AAAs are characterized by inflammation, vascular …

Abdominal aortic aneurysms (AAAs) are a common but asymptomatic disease that has high
susceptibility to rupture. Current therapeutic options are limited to surgical procedures …

Elastin is a vital component of the extracellular matrix, providing soft connective tissues with
the property of elastic recoil following deformation and regulating the cellular response via …

Aortic aneurysms are a common clinical condition that can cause death due to aortic
dissection or rupture. The association between aortic aneurysm pathogenesis and altered …

In the last 10 years, microRNAs (miRNAs) have emerged as critical regulators of numerous
physiological and pathological mechanisms [1-2], including cardiac and vascular smooth …