[HTML][HTML] Phage display-based strategies for cloning and optimization of monoclonal antibodies directed against human pathogens
N Clementi, N Mancini, L Solforosi, M Castelli… - International Journal of …, 2012 - mdpi.com
In the last two decades, several phage display-selected monoclonal antibodies (mAbs) have
been described in the literature and a few of them have managed to reach the clinics …
been described in the literature and a few of them have managed to reach the clinics …
[HTML][HTML] Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites
Acquired immunity in vertebrates maintains polymorphisms in endemic pathogens, leading
to identifiable signatures of balancing selection. To comprehensively survey for genes under …
to identifiable signatures of balancing selection. To comprehensively survey for genes under …
[HTML][HTML] Genomic diversity of the human intestinal parasite Entamoeba histolytica
Background Entamoeba histolytica is a significant cause of disease worldwide. However,
little is known about the genetic diversity of the parasite. We re-sequenced the genomes of …
little is known about the genetic diversity of the parasite. We re-sequenced the genomes of …
Age-dependent IgG subclass responses to Plasmodium falciparum EBA-175 are differentially associated with incidence of malaria in Mozambican children
Plasmodium falciparum blood-stage antigens such as merozoite surface protein 1 (MSP-1),
apical membrane antigen 1 (AMA-1), and the 175-kDa erythrocyte binding antigen (EBA …
apical membrane antigen 1 (AMA-1), and the 175-kDa erythrocyte binding antigen (EBA …
[HTML][HTML] Reduction of multiplicity of infections but no change in msp2 genetic diversity in Plasmodium falciparum isolates from Congolese children after introduction …
R Ibara-Okabande, F Koukouikila-Koussounda… - Malaria journal, 2012 - Springer
Background In this first study conducted after the introduction of artemisinin-combination
therapy (ACT), the major objective was to evaluate Plasmodium falciparum genetic diversity …
therapy (ACT), the major objective was to evaluate Plasmodium falciparum genetic diversity …
Impact of Loci Nature on Estimating Recombination and Mutation Rates in Chlamydia trachomatis
R Ferreira, V Borges, A Nunes… - G3: Genes …, 2012 - academic.oup.com
The knowledge of the frequency and relative weight of mutation and recombination events in
evolution is essential for understanding how microorganisms reach fitted phenotypes …
evolution is essential for understanding how microorganisms reach fitted phenotypes …
Genetic Polymorphism of Plasmodium falciparum Merozoite Surface Protein-1 and -2 and Diversity of Drug Resistance Genes in Blood Donors from Bamako, Mali
BN Thomas, CR Petrella, SR Crespo… - Infectious Diseases …, 2012 - journals.sagepub.com
We examined malaria infection in asymptomatic blood donors from Mali, analyzing allelic
diversity of Plasmodium falciparum (Pf) merozoite surface proteins (msp)-1 and-2 as well as …
diversity of Plasmodium falciparum (Pf) merozoite surface proteins (msp)-1 and-2 as well as …
Stable allele frequency distribution of the polymorphic region of SURFIN4. 2 in Plasmodium falciparum isolates from Thailand
M Kaewthamasorn, K Yahata, JSF Alexandre… - Parasitology …, 2012 - Elsevier
Plasmodium falciparum SURFIN4. 2 (PFD1160w) is a polymorphic protein expressed on the
surface of parasite-infected erythrocytes. Such molecules are expected to be under strong …
surface of parasite-infected erythrocytes. Such molecules are expected to be under strong …
[HTML][HTML] Broadly reactive antibodies specific for Plasmodium falciparum MSP-119 are associated with the protection of naturally exposed children against infection
AE Dent, AM Moormann, CT Yohn, RJ Kimmel… - Malaria Journal, 2012 - Springer
Abstract Background The 19 kDa C-terminal region of Plasmodium falciparum Merozoite
Surface Protein-1 is a known target of naturally acquired humoral immunity and a malaria …
Surface Protein-1 is a known target of naturally acquired humoral immunity and a malaria …
Positive diversifying selection on the Plasmodium falciparum surf4. 1 gene in Thailand
P Xangsayarath, M Kaewthamasorn… - Tropical medicine and …, 2012 - jstage.jst.go.jp
Plasmodium falciparum SURFIN 4.1 is a type I transmembrane protein thought to locate on
the merozoite surface and to be responsible for a reversible adherence to the erythrocyte …
the merozoite surface and to be responsible for a reversible adherence to the erythrocyte …