The basal ganglia network serves to integrate information about context, actions, and
outcomes to shape the behavior of an animal based on its past experience. Clinically, the …

Different striatal projection neurons are the origin of a dual organization essential for basal
ganglia function. We have defined an analogous division of labor in the external globus …

A complex interaction of environmental, genetic and epigenetic factors combine with ageing
to cause the most prevalent of movement disorders Parkinson's disease. Current …

Excessive beta frequency oscillatory and synchronized activity has been reported in the
basal ganglia of parkinsonian patients and animal models of the disease. To gain insight …

It is well established that parkinsonian syndrome is associated with alterations of neuronal
activity temporal pattern basal ganglia (BG). An increase in synchronized oscillations has …

There is substantial evidence supporting a role for the endocannabinoid system as a
modulator of the dopaminergic activity in the basal ganglia, a forebrain system that …

The motor symptoms of Parkinson's disease (PD) are widely thought to arise from an
imbalance in the activity of the two major striatal efferent pathways following the loss of …

Anomalous patterns of synchronization between basal ganglia and cortex underlie the
symptoms of Parkinson's disease. Computational modeling studies suggest that changes in …

Up states are a hallmark of striatal physiology. Spontaneous activity in the thalamo-cortical
network drives robust plateau depolarizations in the medium spiny projection neurons of the …

Auditory P3 amplitude reduction is one of the most robust and replicated findings in
schizophrenia. Recent evidence suggests that these reductions are due to reductions in …