The authors examine the effects of poverty-related adversity on child development, drawing
upon psychobiological principles of experiential canalization and the biological embedding …

Prenatal exposure to maternal stress, anxiety, and depression can have lasting effects on
infant development with risk of psychopathology. Although the impact of prenatal maternal …

Context Our genome adapts to environmental influences, in part through epigenetic
mechanisms, including DNA methylation. Variations in the quality of the early environment …

Children's cognitive abilities and school achievements are deeply affected by parental
socioeconomic status (SES). Numerous studies have reported lower cognitive performance …

Putatively safe and effective for improving cognitive performance in both health and disease,
products purported to train the brain appeal to consumers and healthcare practitioners. In an …

Environmentally induced epigenetic alterations are related to mental health. We investigated
quantitative DNA methylation status before and after an acute psychosocial stressor in two …

Previous studies with nonhuman species have shown that animals exposed to early
adversity show differential DNA methylation relative to comparison animals. The current …

Background: Maternal depression is known to be associated with impairments in child
cognitive development, although the effect of timing of exposure to maternal depression is …

NMDA receptors (NMDARs) are critical to synaptogenesis, neural circuitry and higher
cognitive functions. A hallmark feature of NMDARs is an early postnatal developmental …

Early life is a period of unique sensitivity during which experience can confer enduring
effects on brain structure and function. During early perinatal life the quality of the …