Cell biology of vasopressin-regulated aquaporin-2 trafficking

HB Moeller, RA Fenton - Pflügers Archiv-European Journal of Physiology, 2012 - Springer
Whole-body water balance is predominantly controlled by the kidneys, which have the ability
to concentrate or dilute the urine in the face of altered fluid and solute intake. Regulated …

Regulation of RhoA signaling by the cAMP-dependent phosphorylation of RhoGDIα

A Oishi, N Makita, J Sato, T Iiri - Journal of Biological Chemistry, 2012 - ASBMB
RhoA plays a pivotal role in regulating cell shape and movement. Protein kinase A (PKA)
inhibits RhoA signaling and thereby induces a characteristic morphological change, cell …

Calcium-sensing receptor and aquaporin 2 interplay in hypercalciuria-associated renal concentrating defect in humans. An in vivo and in vitro study

G Procino, L Mastrofrancesco, G Tamma, DR Lasorsa… - PLoS …, 2012 - journals.plos.org
One mechanism proposed for reducing the risk of calcium renal stones is activation of the
calcium-sensing receptor (CaR) on the apical membranes of collecting duct principal cells …

Differential, phosphorylation dependent trafficking of AQP2 in LLC-PK1 cells

WL Rice, Y Zhang, Y Chen, T Matsuzaki, D Brown… - PloS one, 2012 - journals.plos.org
The kidney maintains water homeostasis by modulating aquaporin 2 (AQP2) on the plasma
membrane of collecting duct principal cells in response to vasopressin (VP). VP mediated …

Control of neurite outgrowth by RhoA inactivation

CY Jeon, MY Moon, JH Kim, HJ Kim… - Journal of …, 2012 - Wiley Online Library
J. Neurochem.(2012) 120, 684–698. Abstract cAMP induces neurite outgrowth in the rat
pheochromocytoma cell line 12 (PC12). In particular, di‐butyric cAMP (db‐cAMP) induces a …

Vasopressin: molecular mechanisms of its antidiuretic effect

LN Ivanova - Neuroscience and Behavioral Physiology, 2012 - Springer
The body's water balance is regulated by the neurohypophyseal hormone vasopressin.
Numerous investigators have identified a significant role for aquaporins–water channels in …

[HTML][HTML] Kidney Research and Clinical Practice

HS Hwang - Acta Physiol (Oxf), 2012 - ncbi.nlm.nih.gov
Kidney Res Clin Pract 34 (2015) 188–189 aquaporin-11”[1]. Aquaporin-11 (AQP11) is a new
member of the aquaporin family which was revealed with the completion of the human …

Methods and compositions using oxidized phospholipids

JGN Garcia, K Birukov, N Leitinger… - US Patent App. 13 …, 2012 - Google Patents
The instant invention provides compositions, eg, composi tions comprising oxidized
phospholipids, for the treatment of diseases, disorders and conditions, eg, cute lung injury …

尿濃縮を担うアクアポリン複合体

野田裕美 - 日本薬理学雑誌, 2012 - jstage.jst.go.jp
抄録 アクアポリン 2 (AQP2) は水分子のみを通し, 他には一切の分子を通すことはないという特徴を
もつ水チャネルである. AQP2 は腎臓の集合管で尿濃縮に関わっており, 体内水分量調節を担って …