Computational models of neuron-astrocyte interaction in epilepsy
Astrocytes actively shape the dynamics of neurons and neuronal ensembles by affecting
several aspects critical to neuronal function, such as regulating synaptic plasticity …
several aspects critical to neuronal function, such as regulating synaptic plasticity …
Optogenetic reporters: Fluorescent protein-based genetically encoded indicators of signaling and metabolism in the brain
Fluorescent protein technology has evolved to include genetically encoded biosensors that
can monitor levels of ions, metabolites, and enzyme activities as well as protein …
can monitor levels of ions, metabolites, and enzyme activities as well as protein …
Traumatic alterations in GABA signaling disrupt hippocampal network activity in the developing brain
Severe head trauma causes widespread neuronal shear injuries and acute seizures.
Shearing of neural processes might contribute to seizures by disrupting the transmembrane …
Shearing of neural processes might contribute to seizures by disrupting the transmembrane …
Pyramidal cells accumulate chloride at seizure onset
Seizures are thought to originate from a failure of inhibition to quell hyperactive neural
circuits, but the nature of this failure remains unknown. Here we combine high-speed two …
circuits, but the nature of this failure remains unknown. Here we combine high-speed two …
Roles of aldosterone and oxytocin in abnormalities caused by sevoflurane anesthesia in neonatal rats
W Cao, C Pavlinec, N Gravenstein… - The Journal of the …, 2012 - pubs.asahq.org
Background The authors sought to determine whether subjects with pathophysiological
conditions that are characterized by increased concentrations of aldosterone have …
conditions that are characterized by increased concentrations of aldosterone have …
Rapamycin down-regulates KCC2 expression and increases seizure susceptibility to convulsants in immature rats
Seizure susceptibility to neurological insults, including chemical convulsants, is age-
dependent and most likely reflective of overall differences in brain excitability. The molecular …
dependent and most likely reflective of overall differences in brain excitability. The molecular …
Kainate and Temporal Lobe Epilepsies
Y Ben-Ari - Jasper's basic mechanisms of the epilepsies, 2012 - books.google.com
At the end of July 2010, there were 10,168 references under “kainic acid” and 5149
references under “kainic acid AND neurons” in PubMed. The first reference to kainate1 …
references under “kainic acid AND neurons” in PubMed. The first reference to kainate1 …
Neonatal seizures
DM Olson - NeoReviews, 2012 - publications.aap.org
Neonatal seizures are a common problem encountered or suspected by those caring for
neonates. The estimated incidence of newborns affected is between 0.1% to 0.5%. Because …
neonates. The estimated incidence of newborns affected is between 0.1% to 0.5%. Because …
[HTML][HTML] Neonatal seizures and neuronal transmembrane ion transport
KT Kahle, KJ Staley - 2012 - europepmc.org
Neonatal seizures are a common problem inadequately treated with standard GABAergic
anticonvulsants. Understanding how the ontogeny of neuronal cation/chloride cotransporter …
anticonvulsants. Understanding how the ontogeny of neuronal cation/chloride cotransporter …
Neonatal seizures
R Pressler - Introduction to Epilepsy, 2012 - books.google.com
The term epileptic encephalopathy is not a disease or syndrome designation, but can be
useful when used judiciously. Here it refers to diverse disorders of the brain manifest as the …
useful when used judiciously. Here it refers to diverse disorders of the brain manifest as the …