Circulating microRNAs: a novel class of biomarkers to diagnose and monitor human cancers
K Zen, CY Zhang - Medicinal research reviews, 2012 - Wiley Online Library
Specific and sensitive non‐invasive biomarkers for the detection of human epithelial
malignancies are urgently required to reduce the worldwide morbidity and mortality caused …
malignancies are urgently required to reduce the worldwide morbidity and mortality caused …
The oncogenic role of miR-155 in breast cancer
Abstract miR-155 is an oncogenic miRNA with well described roles in leukemia. However,
additional roles of miR-155 in breast cancer progression have recently been described. A …
additional roles of miR-155 in breast cancer progression have recently been described. A …
A novel miR‐155/miR‐143 cascade controls glycolysis by regulating hexokinase 2 in breast cancer cells
Cancer cells preferentially metabolize glucose through aerobic glycolysis. This
phenomenon, known as the Warburg effect, is an anomalous characteristic of glucose …
phenomenon, known as the Warburg effect, is an anomalous characteristic of glucose …
miR‐155 modulates microglia‐mediated immune response by down‐regulating SOCS‐1 and promoting cytokine and nitric oxide production
AL Cardoso, JR Guedes, L Pereira de Almeida… - …, 2012 - Wiley Online Library
Innate immunity constitutes the first line of defence against both external and endogenous
threats in the brain, and microglia cells are considered key mediators of this process. Recent …
threats in the brain, and microglia cells are considered key mediators of this process. Recent …
MicroRNA alterations of pancreatic intraepithelial neoplasias
Purpose: MicroRNA (miRNA) alterations are likely to contribute to the development of
pancreatic cancer and may serve as markers for the early detection of pancreatic neoplasia …
pancreatic cancer and may serve as markers for the early detection of pancreatic neoplasia …
MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1
Aberrant expression of miR-335 has been frequently reported in cancer studies, suggesting
that there is a close correlation between miR-335 and cancer during its development …
that there is a close correlation between miR-335 and cancer during its development …
[HTML][HTML] Cell-free circulating miRNA biomarkers in cancer
Considerable attention and an enormous amount of resources have been dedicated to
cancer biomarker discovery and validation. However, there are still a limited number of …
cancer biomarker discovery and validation. However, there are still a limited number of …
Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas
I Haecker, LA Gay, Y Yang, J Hu, AM Morse… - 2012 - journals.plos.org
KSHV is the etiological agent of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL),
and a subset of multicentricCastleman's disease (MCD). The fact that KSHV-encoded …
and a subset of multicentricCastleman's disease (MCD). The fact that KSHV-encoded …
Up-regulation of microRNA-155 promotes cancer cell invasion and predicts poor survival of hepatocellular carcinoma following liver transplantation
ZB Han, HY Chen, JW Fan, JY Wu, HM Tang… - Journal of cancer …, 2012 - Springer
Purpose MicroRNAs play important roles in cancer development, progression, and
metastasis. The aim of this study was to determine whether altered microRNA-155 …
metastasis. The aim of this study was to determine whether altered microRNA-155 …
TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death
M Seillier, S Peuget, O Gayet, C Gauthier… - Cell Death & …, 2012 - nature.com
Abstract TP53INP1 (tumor protein 53-induced nuclear protein 1) is a tumor suppressor,
whose expression is downregulated in cancers from different organs. It was described as a …
whose expression is downregulated in cancers from different organs. It was described as a …