Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis

H Tanjore, TS Blackwell… - American Journal of …, 2012 - journals.physiology.org
While the factors that regulate the onset and progression of idiopathic pulmonary fibrosis
(IPF) are incompletely understood, recent investigations have revealed that endoplasmic …

Unravelling the progressive pathophysiology of idiopathic pulmonary fibrosis

A Günther, M Korfei, P Mahavadi… - European …, 2012 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a life-threatening condition, with a median survival of<
3 yrs. The pathophysiology is not fully understood, but chronic injury of alveolar epithelial …

Single ABCA3 Mutations Increase Risk for Neonatal Respiratory Distress Syndrome

JA Wambach, DJ Wegner, K DePass, H Heins… - …, 2012 - publications.aap.org
BACKGROUND AND OBJECTIVE: Neonatal respiratory distress syndrome (RDS) due to
pulmonary surfactant deficiency is heritable, but common variants do not fully explain …

Multiple ways to die: delineation of the unfolded protein response and apoptosis induced by surfactant protein C BRICHOS mutants

JA Maguire, S Mulugeta, MF Beers - … journal of biochemistry & cell biology, 2012 - Elsevier
Epithelial cell dysfunction is now recognized as an important mechanism in the
pathogenesis of interstitial lung diseases. Surfactant Protein C (SP-C), an alveolar type II cell …

New coding in the International Classification of Diseases, Ninth Revision, for children's interstitial lung disease

J Popler, B Lesnick, MK Dishop, RR Deterding - Chest, 2012 - Elsevier
The term “children's interstitial lung disease”(chILD) refers to a heterogeneous group of rare
and diffuse lung diseases associated with significant morbidity and mortality. These …

Генетический анализ вируса гриппа AH1N1" пандемический" в условиях эпидемии

ЕС Кострюкова, НБ Захаржевская, ПА Костин… - Терапевтический …, 2012 - elibrary.ru
Цель исследования. Оценка генетической изменчивости вируса гриппа A НIN1"
пандемический"(ВГА НIN1" пан") в условиях эпидемии и обнаружение набора …

Rare Interstitial Lung Diseases

TJ Huie, AL Olson, MI Schwarz, SK Frankel - Diffuse Lung Disease: A …, 2012 - Springer
This chapter details the clinical presentation, pathophysiology, diagnosis, and management
of pulmonary alveolar proteinosis and lymphangioleiomyomatosis (LAM). It also highlights …

The role of tyrosine kinases in the pathogenesis and treatment of lung disease

J Lam, SJ Levine - Advances in Protein Kinases, 2012 - books.google.com
Tyrosine kinases (TKs) are key regulators of signal transduction pathways that modulate
essential biological processes, such as cellular differentiation, metabolism and proliferation …

[HTML][HTML] A genetic analysis of A H1N1 pandemic influenza virus in the course of the epidemic

ES Kostryukova, NB Zakharzhevskaya… - Terapevticheskii …, 2012 - edgccjournal.org
Aim. To assess genetic variability of A H1N1 pan influenza virus (IV) in the course of the
epidemic and to detect a set of human nucleotide polymorphisms responsible for a severe …

Interstitial lung disease: A case report

SM Kamal, MA Bakar, MA Ahad - Medicine Today, 2012 - banglajol.info
A 65 years old farmer was admitted in Medicine ward with the complaints of progressive
exertional breathlessness, non-productive cough and recurrent episodes of fever. The …