[HTML][HTML] In vitro systems for the study of hepatitis C virus infection
GK Wilson, Z Stamataki - International journal of hepatology, 2012 - hindawi.com
The study of a virus is made possible by the availability of culture systems in which the viral
lifecycle can be realized. Such systems support robust virus entry, replication, assembly, and …
lifecycle can be realized. Such systems support robust virus entry, replication, assembly, and …
Establishment of a novel permissive cell line for the propagation of hepatitis C virus by expression of microRNA miR122
H Kambara, T Fukuhara, M Shiokawa, C Ono… - Journal of …, 2012 - Am Soc Microbiol
The robust cell culture systems for hepatitis C virus (HCV) are limited to those using cell
culture-adapted clones (HCV in cell culture [HCVcc]) and cells derived from the human …
culture-adapted clones (HCV in cell culture [HCVcc]) and cells derived from the human …
Mutations that alter use of hepatitis C virus cell entry factors mediate escape from neutralizing antibodies
I Fofana, S Fafi–Kremer, P Carolla, C Fauvelle… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: The development of vaccines and other strategies to prevent
hepatitis C virus (HCV) infection is limited by rapid viral evasion. HCV entry is the first step of …
hepatitis C virus (HCV) infection is limited by rapid viral evasion. HCV entry is the first step of …
Bile acids specifically increase hepatitis C virus RNA-replication
P Chhatwal, D Bankwitz, J Gentzsch, A Frentzen… - PloS one, 2012 - journals.plos.org
Background Hepatitis C virus (HCV) patients with high serum levels of bile acids (BAs)
respond poorly to IFN therapy. BAs have been shown to increase RNA-replication of …
respond poorly to IFN therapy. BAs have been shown to increase RNA-replication of …
Mechanism (s) of hepatitis C virus induced liver injury
GK Wilson - 2012 - etheses.bham.ac.uk
Hepatitis C virus (HCV) infects hepatocytes of the liver causing progressive liver disease
including; fibrosis, cirrhosis and hepatocellular carcinoma. However, the precise mechanism …
including; fibrosis, cirrhosis and hepatocellular carcinoma. However, the precise mechanism …