Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4)
WT Choi, S Duggineni, Y Xu, Z Huang… - Journal of medicinal …, 2012 - ACS Publications
RECEPTORS Chemokines are small 70 amino acid long soluble proteins that chemoattract
a variety of mononuclear cell types to sites of inflammation or secondary lymphoid organs by …
a variety of mononuclear cell types to sites of inflammation or secondary lymphoid organs by …
Function, diversity and therapeutic potential of the N-terminal domain of human chemokine receptors
M Szpakowska, V Fievez, K Arumugan… - Biochemical …, 2012 - Elsevier
Chemokines and their receptors play fundamental roles in many physiological and
pathological processes such as leukocyte trafficking, inflammation, cancer and HIV-1 …
pathological processes such as leukocyte trafficking, inflammation, cancer and HIV-1 …
Non-amyloidogenic peptide tags for the regulatable self-assembling of protein-only nanoparticles
U Unzueta, N Ferrer-Miralles, J Cedano, X Zikung… - Biomaterials, 2012 - Elsevier
Controlling the self-assembling of building blocks as nanoscale entities is a requisite for the
generation of bio-inspired vehicles for nanomedicines. A wide spectrum of functional …
generation of bio-inspired vehicles for nanomedicines. A wide spectrum of functional …
Subversion of cytokine networks by virally encoded decoy receptors
ML Epperson, CA Lee, DH Fremont - Immunological reviews, 2012 - Wiley Online Library
During the course of evolution, viruses have captured or created a diverse array of open
reading frames, which encode for proteins that serve to evade and sabotage the host innate …
reading frames, which encode for proteins that serve to evade and sabotage the host innate …
A beginner's guide to chemokines
V Vinader, K Afarinkia - Future Medicinal Chemistry, 2012 - Taylor & Francis
This review provides an overview of chemokines and their receptors, with an emphasis on
general features and nomenclature along with a short summary of their properties and …
general features and nomenclature along with a short summary of their properties and …
Peptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4)
S Oishi, N Fujii - Organic & biomolecular chemistry, 2012 - pubs.rsc.org
The development of novel peptide and peptidomimetic ligands for the CXC chemokine
receptor 4 (CXCR4) as therapeutic agents for HIV-1 infection, cancer, and immune system …
receptor 4 (CXCR4) as therapeutic agents for HIV-1 infection, cancer, and immune system …
Reversed binding of a small molecule ligand in homologous chemokine receptors–differential role of extracellular loop 2
PC Jensen, S Thiele, A Steen, A Elder… - British journal of …, 2012 - Wiley Online Library
BACKGROUND AND PURPOSE The majority of small molecule compounds targeting
chemokine receptors share a similar pharmacophore with a centrally located aliphatic …
chemokine receptors share a similar pharmacophore with a centrally located aliphatic …
Focal adhesion kinase is required for KSHV vGPCR signaling
M He, T Bakken, A Kassimova, C Boshoff… - Molecular …, 2012 - Wiley Online Library
Kaposi's sarcoma‐associated herpesvirus (KSHV) is the etiologic agent of Kaposi's
sarcoma, an angiogenic and inflammatory endothelial cell (EC) tumor that is common in …
sarcoma, an angiogenic and inflammatory endothelial cell (EC) tumor that is common in …
[PDF][PDF] 细胞穿膜肽融合蛋白PEP1-vMIP-Ⅱ 促进血管增生研究
狄春红， 罗燕， 杨磊， 尹小菲， 陈佳红… - 中国药学 …, 2012 - journal11.magtechjournal.com
目的构建细胞穿膜肽PEP-1 与vMIP-Ⅱ 融合基因的表达质粒, 原核表达, 纯化并鉴定PEP1-vMIP-
Ⅱ 融合蛋白, 鉴定该蛋白的穿膜功能, 研究其对血管增生相关基因表达的影响 …
Ⅱ 融合蛋白, 鉴定该蛋白的穿膜功能, 研究其对血管增生相关基因表达的影响 …
[HTML][HTML] Novel monoclonal antibodies for identification of multicentric Castleman's disease; Kaposi's sarcoma-associated herpesvirus-encoded vMIP-I and vMIP-II
Recent studies have indicated that vMIP-I and vMIP-II play important roles in the
pathogenesis of Kaposi's sarcoma-associated herpesvirus (KSHV)-related diseases due to …
pathogenesis of Kaposi's sarcoma-associated herpesvirus (KSHV)-related diseases due to …