Neurotransmitters are released by synaptic vesicle exocytosis at the active zone of a
presynaptic nerve terminal. In this review, I discuss the molecular composition and function …

Different types of synapses are specialized to interpret spike trains in their own way by virtue
of the complement of short-term synaptic plasticity mechanisms they possess. Numerous …

Neurotransmitter release is governed by proteins that have homo-logs in most types of
intracellular membrane fusion, including the Sec1/Munc18 protein Munc18-1 and the …

The dynamics of exocytosis are diverse and have been optimized for the functions of
synapses and a wide variety of cell types. For example, the kinetics of exocytosis varies by …

Munc13s are presynaptic proteins that mediate synaptic vesicle priming and thereby control
the size of the readily releasable pool of vesicles. During high synaptic activity, Munc13-1 …

The importance of Ca2+-signaling for many subcellular processes is well established in
higher eukaryotes, whereas information about protozoa is restricted. Recent genome …

The investigation of molecular mechanisms is a fascinating area of current biological
research that unites efforts from scientists with very diverse expertise. This review provides a …

Many regulatory steps precede final membrane fusion in neuroendocrine cells. Some parts
of this preparatory cascade, including fusion and priming, are dependent on the intracellular …

Der sekretorische Zyklus von „large dense core vesicles “(LDCVs) in Chromaffinzellen ist
heute weitestgehend bekannt. LDCVs werden im Zytosol der Zellen mit Neurotransmittern …