Apoptosis modulated by oxidative stress and inflammation during obstructive nephropathy

W Manucha, PG Valles - Inflammation & Allergy-Drug Targets …, 2012 - ingentaconnect.com
Kidney apoptosis and fibrosis are an inevitable outcome of progressive chronic kidney
diseases where congenital obstructive nephropathy is the primary cause of the end-stage …

Fight-or-flight: murine unilateral ureteral obstruction causes extensive proximal tubular degeneration, collecting duct dilatation, and minimal fibrosis

MS Forbes, BA Thornhill, JJ Minor… - American Journal …, 2012 - journals.physiology.org
Unilateral ureteral obstruction (UUO) is the most widely used animal model of progressive
renal disease. Although renal interstitial fibrosis is commonly used as an end point, recent …

Rosuvastatin preserves renal structure following unilateral ureteric obstruction in the neonatal rat

LJ Mazzei, IM García, L Altamirano… - American Journal of …, 2012 - karger.com
Background/Aims: Unilateral ureteric obstruction (UUO) in neonatal rodents can be used as
a paradigm for in utero obstruction in humans and a platform for studying the potential of …

Mechanisms of fetal and neonatal renal impairment by pharmacologic inhibition of angiotensin

RL Chevalier - Current medicinal chemistry, 2012 - ingentaconnect.com
The renin-angiotensin system is highly conserved through evolutionary history, and has
multiple functions in addition to maintaining cardiovascular homeostasis: these include the …

Angiotensin AT1 receptor inhibition-induced apoptosis by RhoA GTPase activation and pERK1/2 signaling pathways in neonatal obstructive nephropathy

V Bocanegra, M Rinaldi Tosi, A Gil Lorenzo… - 2012 - digitum.um.es
Intrarenal renin-Angiotensin system (RAS) activity is increased during early development
and is further enhanced by unilateral ureteral obstruction (UUO). We studied the …

Recoverability of renal functions after relief of partial ureteric obstruction of solitary kidney: impact of ferulic acid

AA Shokeir, AAM Hussein, SA Soliman… - BJU …, 2012 - Wiley Online Library
What's known on the subject? and What does the study add? It is known that the kidney
damage continues even after release of ureteric obstruction. This study found that giving …

[PDF][PDF] COMEINED EFFECT OF" ANGIOTENSIN RECEPTOR BLOCKER, AND ANTIOXIDANTS ON RECOVERAEILITY OF RENAL, FUNCTIONS AF" TER RELIEF" OF …

AAM Hussein, A Abdel-Aziz - RECEPTOR, 2012 - bu.edu.eg
Objectives: To evaluate the effect of a combination ofangiotensin receptor blocker losartan,
and antioxidant Ferulic acid on the recovery of renal function and renal damage afer relief of …