Eye development has been a paradigm for the study of organogenesis, from the
demonstration of lens induction through epithelial tissue morphogenesis, to neuronal …

The PAX proteins derive their name from the" paired box," a region of homology first
described between the Drosophila paired (Prd) and gooseberry (Gsb) proteins and later …

Waardenburg syndrome (WS) is an auditory–pigmentary disorder resulting from melanocyte
defects, with varying combinations of sensorineural hearing loss and abnormal pigmentation …

Pax6 is a member of the Pax family of transcription factors that contains a DNA binding
paired-box and homeobox domain. In animals, including humans, Pax6 plays a key role in …

Nature has illustrated through numerous examples that protein dimerization has structural
and functional advantages. We previously reported the design and characterization of an …

The homeodomain-containing transcription factor Pitx2 (pituitary homeobox protein 2) is
present in many developing embryonic tissues, including the heart. Its homeodomain is …

2014-05-20 Assigned to MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
reassignment MUSC FOUNDATION FOR RESEARCH DEVELOPMENT ASSIGNMENT OF …

Table of Contents Page 1 MIR-7 TARGETS PAX6 AND MODULATES BLADDER CANCER
CELL MIGRATION By Renaud Quantin A thesis submitted to the University of Monash For the …

Zusammenfassung Der Typ 2 Diabetes mellitus ist heute angesichts seiner global
zunehmenden Inzidenzrate eine der häufigsten endokrinen Stoffwechselerkrankungen des …

Differentiation of pituitary progenitors into the six different hormone-producing cell types that
form the mature organ is a complex process that requires the coordinated spatial and …