Rationale Pathological gambling (PG) has recently been considered as a “behavioral” or
nonsubstance addiction. A comparison of the characteristics of PG and substance use …

Patients with on-line game addiction (POGA) and professional video game players play
video games for extended periods of time, but experience very different consequences for …

Excessive computer gaming has recently been proposed as a possible pathological illness.
However, research on this topic is still in its infancy and underlying neurobiological …

Alcohol‐associated cues are able to elicit brain activations in mesocorticolimbic networks
that are related to the rewarding properties of the drug. Some authors hypothesize that the …

The use of translational noninvasive neuroimaging has revealed that drug addiction and
obesity share striking similarities in functional impairment in discrete brain regions and …

Cocaine addiction is characterized by compulsive drug seeking, including relapse after a
period of withdrawal. The relapse response requires increased glutamate transmission in …

Abnormalities in frontostriatal systems are thought to be central to the pathophysiology of
addiction, and may underlie the maladaptive processing of the highly generalizable …

Drug addiction is characterized by dysregulated dopamine neurotransmission. Although
dopamine functioning appears to partially recover with abstinence, the specific regions that …

BACKGROUND: Chronic cocaine use is associated with neurobiological and cognitive
deficits that persist into abstinence, hindering success of behavioral treatment strategies and …

This chapter highlights the use of nonhuman primate models of cocaine addiction and the
use of positron emission tomography (PET) imaging to study the role of individual …