Elevated immune-inflammatory signaling in mood disorders: a new therapeutic target?
RK McNamara, FE Lotrich - Expert review of neurotherapeutics, 2012 - Taylor & Francis
Converging translational evidence has implicated elevated immune-inflammatory signaling
activity in the pathoetiology of mood disorders, including major depressive disorder and …
activity in the pathoetiology of mood disorders, including major depressive disorder and …
Inflammation in psychopathology of depression: clinical, biological, and therapeutic implications
KP Su - BioMedicine, 2012 - Elsevier
Increasing evidence suggests that inflammation responses play an important role in the
pathophysiology of depression. Clinically depressed patients manifest higher levels of …
pathophysiology of depression. Clinically depressed patients manifest higher levels of …
[HTML][HTML] Associations between n− 3 PUFA concentrations and cognitive function after recovery from late-life depression
Background: Lower concentrations of n− 3 PUFAs have been reported to be associated with
cognitive impairment and dementia, but also with depression—itself a potential risk factor for …
cognitive impairment and dementia, but also with depression—itself a potential risk factor for …
Imaging brain signal transduction and metabolism via arachidonic and docosahexaenoic acid in animals and humans
M Basselin, E Ramadan, SI Rapoport - Brain research bulletin, 2012 - Elsevier
The polyunsaturated fatty acids (PUFAs), arachidonic acid (AA, 20: 4n− 6) and
docosahexaenoic acid (DHA, 22: 6n− 3), important second messengers in brain, are …
docosahexaenoic acid (DHA, 22: 6n− 3), important second messengers in brain, are …
Associations of polyunsaturated fatty acids with residual depression or anxiety in older people with major depression
A Jadoon, CC Chiu, L McDermott… - Journal of affective …, 2012 - Elsevier
BACKGROUNDS: Depression in late life often follows a chronic course with residual
depressive and anxiety symptoms. Levels of omega-3 polyunsaturated fatty acids (PUFAs) …
depressive and anxiety symptoms. Levels of omega-3 polyunsaturated fatty acids (PUFAs) …
Omega-3 fatty acid deficiency augments risperidone-induced hepatic steatosis in rats: positive association with stearoyl-CoA desaturase
RK McNamara, IJ Magrisso, R Hofacer… - Pharmacological …, 2012 - Elsevier
Psychiatric patients frequently exhibit long-chain n− 3 (LCn− 3) fatty acid deficits and
elevated triglyceride (TAG) production following chronic exposure to second generation …
elevated triglyceride (TAG) production following chronic exposure to second generation …
Cardiovascular Risk in Tunisian Patients with Bipolar I Disorder
A Ezzaher, DH Mouhamed, A Mechri… - … -From Prevention to …, 2012 - books.google.com
Bipolar disorder (previously also labeled manic-depressive illness) is typically referred to as
an episodic, yet lifelong and clinically severe affective (or mood) disorder, affecting …
an episodic, yet lifelong and clinically severe affective (or mood) disorder, affecting …
Therapeutic use of compounds
RSB Williams, M Walker - 2012 - Google Patents
A compound having the formula (I) R1-COOH wherein R1 is an alkyl or alkenyl group having
a C 7-11 backbone, optionally branched with a C 1-6 alkyl group at any C position in the …
a C 7-11 backbone, optionally branched with a C 1-6 alkyl group at any C position in the …
Chapter The role of fish oil in managing
AM Rees, G Parker - Bipolar II Disorder: Modelling, Measuring …, 2012 - books.google.com
As noted in Chapter 6, there is evidence suggesting that the prevalence of Bipolar II disorder
(BP II) is increasing. Any suggested increase could be artefactual, reflecting changes in …
(BP II) is increasing. Any suggested increase could be artefactual, reflecting changes in …