The genetics of multiple sclerosis: an up‐to‐date review
Multiple sclerosis (MS) is a prevalent inflammatory disease of the central nervous system
that often leads to disability in young adults. Treatment options are limited and often only …
that often leads to disability in young adults. Treatment options are limited and often only …
Genetic background of multiple sclerosis
AD Sadovnick - Autoimmunity reviews, 2012 - Elsevier
Multiple sclerosis (MS) is a one of the group of diseases labeled as “common complex”.
Virtually all common complex traits, genetic and environmental components have important …
Virtually all common complex traits, genetic and environmental components have important …
Progress in multiple sclerosis genetics
A Goris, I Pauwels, B Dubois - Current genomics, 2012 - ingentaconnect.com
A genetic component in the susceptibility to multiple sclerosis (MS) has long been known,
and the first and major genetic risk factor, the HLA region, was identified in the 1970's …
and the first and major genetic risk factor, the HLA region, was identified in the 1970's …
Polymorphisms in the genes coding for iron binding and transporting proteins are associated with disability, severity, and early progression in multiple sclerosis
D Gemmati, G Zeri, E Orioli, FE De Gaetano… - BMC medical …, 2012 - Springer
Background Iron involvement/imbalance is strongly suspected in multiple sclerosis (MS)
etiopathogenesis, but its role is quite debated. Iron deposits encircle the veins in brain MS …
etiopathogenesis, but its role is quite debated. Iron deposits encircle the veins in brain MS …
Replication study of multiple sclerosis (MS) susceptibility alleles and correlation of DNA-variants with disease features in a cohort of Austrian MS patients
MC Schmied, S Zehetmayer, M Reindl, R Ehling… - Neurogenetics, 2012 - Springer
We performed a replication study in 883 Austrian multiple sclerosis (MS) patients and 972
control individuals for 25 previously risk-associated loci (39 SNPs). Two loci, rs1109670 …
control individuals for 25 previously risk-associated loci (39 SNPs). Two loci, rs1109670 …
The influence of the HLA‐DRB1 and HLA‐DQB1 allele heterogeneity on disease risk and severity in Iranian patients with multiple sclerosis
A Kollaee, M Ghaffarpor, HA Ghlichnia… - International Journal …, 2012 - Wiley Online Library
Multiple sclerosis (MS) is a common autoimmune disorder of the central nervous system.
Recent studies have shown that the HLA‐DRB1 and DQB1 alleles are associated with MS …
Recent studies have shown that the HLA‐DRB1 and DQB1 alleles are associated with MS …
DRB1*03:01 Haplotypes: Differential Contribution to Multiple Sclerosis Risk and Specific Association with the Presence of Intrathecal IgM Bands
EG de La Concha, ML Cavanillas, MC Cenit, E Urcelay… - PloS one, 2012 - journals.plos.org
Background Multiple sclerosis (MS) is a multifactorial disease with a genetic basis. The
strongest associations with the disease lie in the Human Leukocyte Antigen (HLA) region …
strongest associations with the disease lie in the Human Leukocyte Antigen (HLA) region …
Frequency of HLA-DRB1 gene alleles in patients with multiple sclerosis in a Lithuanian population
The aim of the present study was to investigate the influence of HLA-DRB1 alleles on the
genetic susceptibility to multiple sclerosis in the Lithuanian population. Material and …
genetic susceptibility to multiple sclerosis in the Lithuanian population. Material and …
From genes to characteristics of multiple sclerosis
HF Harbo, IL Mero - Acta Neurologica Scandinavica, 2012 - Wiley Online Library
Multiple sclerosis (MS) is an inflammatory, demyelinating heterogeneous disease of the
central nervous system, probably caused by an interaction of common genetic and …
central nervous system, probably caused by an interaction of common genetic and …
[PDF][PDF] Imunogenetinių veiksnių reikšmė sergančiųjų išsėtine skleroze ligos eigos formai ir negaliai
R Balnytė - 2012 - lsmu.lt
IS–išsėtinė sklerozė CNS–centrinė nervų sistema MRT–magnetinio rezonanso tomografija
PI–pasikliautinasis intervalas GS–galimybių santykis SN–standartinis nuokrypis SP …
PI–pasikliautinasis intervalas GS–galimybių santykis SN–standartinis nuokrypis SP …