Chemical reactivity and skin sensitization potential for benzaldehydes: can Schiff base formation explain everything?

A Natsch, H Gfeller, T Haupt… - Chemical Research in …, 2012 - ACS Publications
Skin sensitizers chemically modify skin proteins rendering them immunogenic. Sensitizing
chemicals have been divided into applicability domains according to their suspected …

Electrochemistry/mass spectrometry as a tool in the investigation of the potent skin sensitizer p‐phenylenediamine and its reactivity toward nucleophiles

S Jahn, H Faber, R Zazzeroni… - … Communications in Mass …, 2012 - Wiley Online Library
RATIONALE Although para‐phenylenediamine (PPD) is known to cause severe allergic
contact dermatitis in consequence of autoxidation and/or skin metabolism pathways, it is …

Electrochemistry/liquid chromatography/mass spectrometry to demonstrate irreversible binding of the skin allergen p‐phenylenediamine to proteins

S Jahn, H Faber, R Zazzeroni… - … Communications in Mass …, 2012 - Wiley Online Library
RATIONALE para‐Phenylenediamine (PPD) is a potent and well‐known allergen, which is
commonly used in hair or fur dyes and can cause severe allergic contact dermatitis. In this …