Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex
M Kuroiwa, GL Snyder, T Shuto, A Fukuda… - …, 2012 - Springer
Rationale Alteration of dopamine neurotransmission in the prefrontal cortex, especially
hypofunction of dopamine D1 receptors, contributes to psychotic symptoms and cognitive …
hypofunction of dopamine D1 receptors, contributes to psychotic symptoms and cognitive …
Modeling of spatially‐restricted intracellular signaling
SR Neves - Wiley Interdisciplinary Reviews: Systems Biology …, 2012 - Wiley Online Library
Understanding the signaling capabilities of a cell presents a major challenge, not only due
to the number of molecules involved, but also because of the complex network connectivity …
to the number of molecules involved, but also because of the complex network connectivity …
PDE4 control on cAMP/PKA compartmentation revealed by biosensor imaging in neurons
P Vincent, LRV Castro, N Gervasi… - Hormone and …, 2012 - thieme-connect.com
Electrophysiological recordings (using the slow-AHP potassium current) together with novel
biosensor imaging methods (with AKAR and Epac sensors) were used in preparations of …
biosensor imaging methods (with AKAR and Epac sensors) were used in preparations of …
Imaging PKA activation inside neurons in brain slice preparations
M Brito, E Guiot, P Vincent - Protein Kinase Technologies, 2012 - Springer
Cyclic-AMP dependent protein kinase (PKA) is present in most branches of the living
kingdom, and as an example in the nervous system where PKA integrates the cellular effects …
kingdom, and as an example in the nervous system where PKA integrates the cellular effects …